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Drug Interaction Report

1 potential interaction and/or warning found for the following 2 drugs:

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Interactions between your drugs

Major

dexAMETHasone iohexol

Applies to: Dalalone DP (dexamethasone), Omnipaque 350 (iohexol)

CONTRAINDICATED: Coadministration of corticosteroids with iodinated contrast media by the intrathecal route may be associated with a high incidence of radiographic arachnoiditis. Meningitis and seizures may also occur.

MANAGEMENT: Intrathecal coadministration of corticosteroids with iodinated contrast media is considered contraindicated.

References

  1. (2001) "Product Information. Amipaque (metrizamide)." Nycomed Inc
  2. (2001) "Product Information. Osmovist 240 (iotrolan)." Berlex Canada Inc
  3. (2007) "Product Information. Omnipaque 180 (iohexol)." Amersham Health
  4. (2007) "Product Information. Isovue-M-200 (iopamidol)." Bracco Diagnostics Inc
  5. Nelson DA, Landau WM (2001) "Intraspinal steroids: history, efficacy, accidentality, and controversy with review of United States Food and Drug Administration reports." J Neurol Neurosurg Psychiatry, 70, p. 433-43
View all 5 references

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Drug and food interactions

No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No duplication warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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