Drug Interaction Report

Talk to your doctor before using vitamin E together with givinostat. Regular use of antioxidant supplements including vitamin E may reduce the effectiveness of givinostat and other cancer treatments including radiation therapy. In addition, taking excessive amounts of vitamin E may cause harm to your heart. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Food increases the absorption of givinostat. To ensure adequate blood levels of the medication, givinostat should be administered with food. Additionally, food can help mask the bitter taste of the oral suspension. Follow up with your healthcare professional if you have any additional questions.