Drug Interaction Report
3 potential interactions and/or warnings found for the following 2 drugs:
- butabarbital
- Phenytoin Sodium, Prompt (phenytoin)
Interactions between your drugs
phenytoin butabarbital
Applies to: Phenytoin Sodium, Prompt (phenytoin), butabarbital
Using phenytoin together with butabarbital may affect your seizure control. You may need dose adjustments or special tests in order to safely take both medications together. This combination may alter phenytoin levels. You should notify your doctor if you have a loss of seizure control or possible symptoms such as nausea, vomiting, tremors, loss of muscle coordination, lethargy, slurred speech, visual disturbances, or changes in mental status. It is important that you tell your healthcare provider about all other medications that you are using including vitamins and herbs. Do not stop using your medications without first talking to your doctor.
Drug and food interactions
butabarbital food
Applies to: butabarbital
Ask your doctor before using butabarbital together with ethanol, this can add to dizziness, drowsiness and other side effects of butabarbital. Be careful if you drive or do activities that require you to be awake and alert. Talk with your doctor before using any medications together, or drinking alcohol with butabarbital. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
phenytoin food
Applies to: Phenytoin Sodium, Prompt (phenytoin)
Phenytoin levels may decrease when the suspension is given with enteral feedings. This could lead to a loss of seizure control. You could interrupt the feeding for 2 hours before and after the phenytoin dose. Alternatively, you may give the phenytoin suspension diluted in water and flush the tube with water after administration. These would make it easier for your body to absorb the medication. However, this still may not entirely avoid the interaction and may not always be feasible. You should have your phenytoin levels checked upon starting and stopping of enteral feedings. In addition, using phenytoin together with food may alter the effects of phenytoin. Contact your doctor if you experience worsening of seizure control or symptoms of toxicity, including twitching eye movements, slurred speech, loss of balance, tremor, muscle stiffness or weakness, nausea, vomiting, feeling light-headed, fainting, and slow or shallow breathing. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Ask your doctor before making any changes to your therapy.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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