Drug Interaction Report
8 potential interactions and/or warnings found for the following 2 drugs:
- Dristan Cold Multi Symptom Formula (acetaminophen / chlorpheniramine / phenylephrine)
- Genora 1/50 (mestranol / norethindrone)
Interactions between your drugs
acetaminophen mestranol
Applies to: Dristan Cold Multi Symptom Formula (acetaminophen / chlorpheniramine / phenylephrine), Genora 1 / 50 (mestranol / norethindrone)
Information for this minor interaction is available on the professional version.
Drug and food interactions
acetaminophen food
Applies to: Dristan Cold Multi Symptom Formula (acetaminophen / chlorpheniramine / phenylephrine)
Ask your doctor before using acetaminophen together with ethanol. This can cause serious side effects that affect your liver. Call your doctor immediately if you experience a fever, chills, joint pain or swelling, excessive tiredness or weakness, unusual bleeding or bruising, skin rash or itching, loss of appetite, nausea, vomiting, or yellowing of the skin or the whites of your eyes. If your doctor does prescribe these medications together, you may need a dose adjustment or special tests to safely take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
chlorpheniramine food
Applies to: Dristan Cold Multi Symptom Formula (acetaminophen / chlorpheniramine / phenylephrine)
Alcohol can increase the nervous system side effects of chlorpheniramine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with chlorpheniramine. Do not use more than the recommended dose of chlorpheniramine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.
norethindrone food
Applies to: Genora 1/50 (mestranol / norethindrone)
Grapefruit juice may increase the blood levels of certain medications such as norethindrone. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with norethindrone. However, if you have been regularly consuming grapefruit or grapefruit juice with the medication, then it is advisable for you to talk with your doctor before changing the amounts of these products in your diet, as this may alter the effects of your medication. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.
phenylephrine food
Applies to: Dristan Cold Multi Symptom Formula (acetaminophen / chlorpheniramine / phenylephrine)
Both phenylephrine and caffeine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
mestranol food
Applies to: Genora 1/50 (mestranol / norethindrone)
Information for this minor interaction is available on the professional version.
norethindrone food
Applies to: Genora 1/50 (mestranol / norethindrone)
Information for this minor interaction is available on the professional version.
mestranol food
Applies to: Genora 1/50 (mestranol / norethindrone)
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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