Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- Benzamycin Pak (benzoyl peroxide / erythromycin topical)
- dapsone topical
Interactions between your drugs
benzoyl peroxide topical dapsone topical
Applies to: Benzamycin Pak (benzoyl peroxide / erythromycin topical), dapsone topical
In one clinical study, topical application of dapsone followed by benzoyl peroxide in subjects with acne vulgaris was associated with a temporary local yellow or orange discoloration of the skin and facial hair in 7 out of 95 subjects, with resolution in 4 to 57 days. The mechanism of interaction is unknown.
References (1)
- (2005) "Product Information. Aczone (dapsone topical)." QLT USA, Inc
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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