Drug Interaction Report
2 potential interactions and/or warnings found for the following 2 drugs:
- Cemill 500 (ascorbic acid)
- fluphenazine
Interactions between your drugs
fluPHENAZine ascorbic acid
Applies to: fluphenazine, Cemill 500 (ascorbic acid)
A case report suggests that ascorbic acid may reduce the therapeutic effect of fluphenazine.
References (1)
- Dysken MW, Cumming RJ, Channon RA, Davis JM (1979) "Drug interaction between ascorbic acid and fluphenazine." JAMA, 241, p. 2008
Drug and food interactions
fluPHENAZine food
Applies to: fluphenazine
GENERALLY AVOID: Concurrent use of ethanol and phenothiazines may result in additive CNS depression and psychomotor impairment. Also, ethanol may precipitate dystonic reactions in patients who are taking phenothiazines. The two drugs probably act on different sites in the brain, although the exact mechanism of the interaction is not known.
MANAGEMENT: Patients should be advised to avoid alcohol during phenothiazine therapy.
References (2)
- Lutz EG (1976) "Neuroleptic-induced akathisia and dystonia triggered by alcohol." JAMA, 236, p. 2422-3
- Freed E (1981) "Alcohol-triggered-neuroleptic-induced tremor, rigidity and dystonia." Med J Aust, 2, p. 44-5
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Ester-C
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Phospho-Trin 250 Neutral
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Vitamin C TR
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Cemill 1000
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Potassium phosphate/sodium phosphate
Potassium phosphate/sodium phosphate is used for hypophosphatemia, urinary acidification
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Further information
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