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Drug Interaction Report

2 potential interactions and/or warnings found for the following 2 drugs:

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Interactions between your drugs

Moderate

cosyntropin triamcinolone

Applies to: cosyntropin, Clinalog (triamcinolone)

ADJUST DOSING INTERVAL: The accuracy of cosyntropin as a diagnostic agent in the screening of adrenocortical insufficiency may be impaired by concomitant use of glucocorticoids. Glucocorticoids may falsely elevate plasma cortisol levels, which may lead to inaccurate results following the administration of cosyntropin.

MANAGEMENT: Clinicians should be aware of the potential for inaccurate results when administering a cosyntropin test to patients on concomitant therapy with glucocorticoids. Some authorities recommend withholding the glucocorticoid on the day of testing. Long-acting glucocorticoids may need to be withheld for a longer period before cosyntropin testing. Local protocols and/or the manufacturer's product labeling should be consulted for specific guidance.

References (2)
  1. (2001) "Product Information. Cortrosyn (cosyntropin)." Organon
  2. (2018) "Product Information. Cosyntropin (cosyntropin)." Sandoz Inc

Drug and food interactions

No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.

Duplication

Cortisones

Therapeutic duplication

The recommended maximum number of medicines in the 'cortisones' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'cortisones' category:

  • Clinalog (triamcinolone)
  • cosyntropin

Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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