Drug Interaction Report
3 potential interactions and/or warnings found for the following 2 drugs:
- Biothrax (anthrax vaccine adsorbed)
- letrozole / ribociclib
Interactions between your drugs
letrozole ribociclib
Applies to: letrozole / ribociclib, letrozole / ribociclib
Ribociclib may increase the blood levels and effects of letrozole. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
anthrax vaccine adsorbed ribociclib
Applies to: Biothrax (anthrax vaccine adsorbed), letrozole / ribociclib
If you are currently being treated or have recently been treated with ribociclib, you should let your doctor know before receiving anthrax vaccine adsorbed. Depending on the dose and length of time you have been on ribociclib, you may have a reduced response to the vaccine. In some situations, your doctor may want to delay vaccination to give your body time to recover from the effects of ribociclib therapy. If you have recently been vaccinated with anthrax vaccine adsorbed, your doctor may choose to postpone treatment with ribociclib for a couple of weeks or more. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
ribociclib food
Applies to: letrozole / ribociclib
Patients should not consume pomegranates, pomegranate juice, grapefruit, or grapefruit juice during treatment with ribociclib unless directed otherwise by your doctor. Pomegranate juice or grapefruit juice can increase the blood levels of ribociclib. You may be more likely to experience side effects such as nausea; vomiting; diarrhea; loss of appetite; abdominal pain; mouth sores; hair loss; weakness; and impaired bone marrow function resulting in low numbers of different types of blood cells, which can increase the risk of anemia, bleeding problems, and infections. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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