Drug Interaction Report
4 potential interactions and/or warnings found for the following 2 drugs:
- methoxsalen
- Oreticyl 50 (deserpidine / hydrochlorothiazide)
Interactions between your drugs
hydroCHLOROthiazide methoxsalen
Applies to: Oreticyl 50 (deserpidine / hydrochlorothiazide), methoxsalen
Methoxsalen sensitizes your skin to sunlight, and combining it with other medications that can also have this effect (i.E., photosensitivity) such as hydroCHLOROthiazide may increase the risk of a severe sunburn. Check with your doctor to see if you should temporarily withhold any of your medications before and after treatment with methoxsalen. Following treatment, you should avoid exposure of the eyes and skin to sunlight or artificial UV rays (e.G., sunlamps or tanning beds ) for at least 24 hours. If sun exposure is unavoidable, you should use suitable covering (e.G., hat and gloves, long-sleeved clothing) or a topical sunscreen (SPF 15 or higher), along with wrap-around UVA- absorbing sunglasses to prevent cataracts, for the 24 hour period following treatment, whether exposed to direct or indirect sunlight in the open or through a window glass. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
hydroCHLOROthiazide deserpidine
Applies to: Oreticyl 50 (deserpidine / hydrochlorothiazide), Oreticyl 50 (deserpidine / hydrochlorothiazide)
Before taking hydroCHLOROthiazide, tell your doctor if you also use deserpidine. You may need dose adjustments or special tests in order to safely take both medications together. The blood pressure lowering effects of this combination may be additive. You should take deserpidine at bedtime and to notify your doctor if have dizziness or feel faint. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
methoxsalen food
Applies to: methoxsalen
Methoxsalen should be administered with food or milk. This may make it easier for your body to tolerate the medication. Avoid eating or coming in contact with limes, figs, parsley, parsnips, rue (Ruta graveolens), mustard, carrots and celery. This can increase the risk of photosensitivity and cause your skin to burn more easily. Avoid prolonged exposure to sunlight, sunlamps, or tanning beds. Methoxsalen make your skin more sensitive to sunlight, and a sunburn may result. Wear protective clothing and use a sunscreen if you must be in the sun. Call your doctor if you have severe burning, redness, itching, rash, or swelling after being in the sun.
hydroCHLOROthiazide food
Applies to: Oreticyl 50 (deserpidine / hydrochlorothiazide)
HydroCHLOROthiazide and ethanol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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