Drug Interaction Report
2 potential interactions and/or warnings found for the following 2 drugs:
- Constilac (lactulose)
- Fiberall (psyllium)
Interactions between your drugs
psyllium lactulose
Applies to: Fiberall (psyllium), Constilac (lactulose)
GENERALLY AVOID: In the treatment of portal-systemic encephalopathy, the loose stools produced by concomitant use of other laxatives may falsely suggest that adequate lactulose dosage has been achieved.
MANAGEMENT: The use of other laxatives should generally be avoided when lactulose is prescribed for portal-systemic encephalopathy, especially during the initial phase of therapy.
References
- (2002) "Product Information. Chronulac (lactulose)." Hoechst Marion Roussel
- (2002) "Product Information. Cephulac (lactulose)." Hoechst Marion Roussel
- (2012) "Product Information. Enulose (lactulose)." United Research Laboratories/Mutual Pharmaceutical Company
- (2019) "Product Information. Generlac (lactulose)." Morton Grove Pharmaceuticals Inc
Drug and food interactions
psyllium food
Applies to: Fiberall (psyllium)
ADJUST DOSING INTERVAL: Bulk-forming laxatives such as guar gum, psyllium, polycarbophil, or methylcellulose may affect the bioavailability of concomitantly administered substances due to their effect on the rate of gastrointestinal transit and gastric emptying.
MANAGEMENT: In general, oral medications should be administered at least 2 hours before or 2 hours after dosing of the bulk-forming laxative.
References
- (2001) "Product Information. Metamucil (psyllium)." Procter and Gamble Pharmaceuticals
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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