Drug Interaction Report
2 potential interactions and/or warnings found for the following 2 drugs:
- Ifex/Mesnex (ifosfamide / mesna)
- Zagam (sparfloxacin)
Interactions between your drugs
ifosfamide sparfloxacin
Applies to: Ifex/Mesnex (ifosfamide / mesna), Zagam (sparfloxacin)
Information for this minor interaction is available on the professional version.
Drug and food interactions
ifosfamide food
Applies to: Ifex/Mesnex (ifosfamide / mesna)
Do not consume grapefruit or grapefruit juice while you are receiving treatment with ifosfamide, as this may decrease the anticancer effects of ifosfamide and may increase its adverse effects on your nervous system and your kidneys. Do not use alcohol while you are receiving treatment with ifosfamide. This may increase nervous system side effects such as somnolence, dizziness, confusion, difficulty concentrating, and impairment of thinking and judgment; and may also increase nausea and vomiting. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. Also, avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medication without first talking to your doctor.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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