Skip to Content

Voraxaze Approval History

  • FDA approved: Yes (First approved January 17th, 2012)
  • Brand name: Voraxaze
  • Generic name: glucarpidase
  • Dosage form: Injection
  • Company: BTG International Inc.
  • Treatment for: Methotrexate Overdosage

Voraxaze (glucarpidase) is a carboxypeptidase enzyme indicated for the treatment of toxic plasma methotrexate levels in patients with delayed methotrexate clearance due to impaired renal function.

Development History and FDA Approval Process for Voraxaze

Jan 17, 2012Approval FDA Approves Voraxaze to Treat Patients with Toxic Methotrexate Levels
Nov 20, 2008Protherics PLC Voraxaze Rolling BLA Submission Initiated with the US FDA

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.