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Yellow Fever Vaccine Injection

Last Updated: December 15, 2017
Status: Current

Yellow Fever Vaccine Injection

Products Affected - Description
  • YF-Vax subcutaneous powder for suspension for injection, Sanofi Pasteur
    Multiple-dose vial (5 doses per vial) with diluent 1 count (NDC 49281-0915-05)

Single-dose vial with diluent, 5 count (NDC 49281-0915-01)
Reason for the Shortage
    • Sanofi Pasteur states the shortage is due to production delays.1
    • There are no other suppliers of yellow fever vaccine.
    • Additional information on the yellow fever shortage.
Available Products
  • There are no presentations available

Estimated Resupply Dates

    • Sanofi Pasteur has YF-Vax multi-dose vials and single dose vials on back order and the company estimates a release date in mid-2018.1
    • FDA accepted an investigational new drug application in October 2016. This is for the importation of another yellow fever vaccine from France. The trade name of the imported product is Stamaril.

Implications for Patient Care

  • Yellow fever vaccine must be used within 1 hour of reconstitution. Practitioners should consider scheduling several patients for immunization simultaneously to conserve use of YF-Vax 5-dose vials.2

Alternative Agents & Management

  • Information on countries that require yellow fever vaccination.


    1. Sanofi Pasteur, Customer Service (personal communication). November 24 and December 15, 2015; January 13, February 3, March 22, April 18, May 31, July 20, September 27, and November 29, 2016; January 31, March 27, June 27, August 29, November 1, and December 15, 2017.
    2. Yellow Fever Vaccine (YF-Vax). Product information. Swiftwater, PA: Sanofi Pasteur, 2014 March.


Updated December 15, 2017 by Leslie Jensen, PharmD, Drug Information Specialist. Created November 24, 2015 by Leslie Jensen, PharmD, Drug Information Specialist. Copyright 2017, Drug Information Service, University of Utah, Salt Lake City, UT.