Promethazine Injection Shortage
Last Updated: March 21, 2025
Status: Current
Products Affected - Description
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- Phenergan injection, Hikma, 25 mg/mL, 1 mL vial, 25 count, NDC 00641-6084-25
- Promethazine injection, Hikma, 25 mg/mL, 1 mL vial, 25 count, NDC 00641-0928-25
Reason for the Shortage
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- Hikma has promethazine injection on shortage due to increased demand.
- X-Gen has promethazine injection available.
Available Products
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- Phenergan injection, Hikma, 25 mg/mL, 1 mL ampule, 25 count, NDC 00641-6082-25
- Phenergan injection, Hikma, 50 mg/mL, 1 mL ampule, 25 count, NDC 00641-6083-25
- Phenergan injection, Hikma, 50 mg/mL, 1 mL vial, 25 count, NDC 00641-6085-25
- Promethazine injection, Hikma, 25 mg/mL, 1 mL ampule, 25 count, NDC 00641-1495-35
- Promethazine injection, Hikma, 50 mg/mL, 1 mL ampule, 25 count, NDC 00641-1496-35
- Promethazine injection, Hikma, 50 mg/mL, 1 mL vial, 25 count, NDC 00641-0929-25
- Promethazine injection, X-Gen, 25 mg/mL, 1 mL ampule, 25 count, NDC 39822-5525-03
- Promethazine injection, X-Gen, 50 mg/mL, 1 mL ampule, 25 count, NDC 39822-5550-06
Estimated Resupply Dates
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- Hikma has promethazine 25 mg/mL 1 mL vials on back order and the company cannot estimate a release date.
- Hikma has Phenergan 25 mg/mL 1 mL vials on back order and the company cannot estimate a release date.
Safety
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- ISMP has a list of recommendations in the 2018-2019 Targeted Medication Safety Best Practices for Hospitals including the removal of promethazine from hospitals. Detailed information can be found at https://www.ismp.org/sites/default/files/attachments/2019-01/TMSBP-for-Hospitalsv2.pdf.
Updated
Updated March 21, 2025 by Michelle Wheeler, PharmD, Drug Information Specialist. Created September 29, 2022 by Michelle Wheeler, PharmD, Drug Information Specialist. © 2025, Drug Information Service, University of Utah, Salt Lake City, UT.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.