Pentamidine Isethionate Shortage

• • Fresenius Kabi had Nebupent and Pentam 300 on back order due to a short-term manufacturer delay.
  • Seton Pharmaceuticals had pentamidine isethionate injection on shortage due to high demand.

• • NebuPent lyophilized powder for inhalation, Fresenius Kabi, 300 mg, 15 mL single dose vial, NDC 63323-0877-15
  • Pentam 300 lyophilized powder for injection, Fresenius Kabi, 300 mg, single dose vial, 10 count, NDC 63323-0113-10
  • Pentamidine isethionate lyophilized powder for inhalation, Seton Pharmaceuticals, 300 mg, single dose vial, 10 count, NDC 13925-0522-01
  • Pentamidine isethionate lyophilized powder for injection, Seton Pharmaceuticals, 300 mg, single dose vial, 10 count, NDC 13925-0515-10

Estimated Resupply Dates

• • All marketed presentations are available.

Implications for Patient Care

• • Some clinicians may choose to use Pentam off-label via the nebulized route or NebuPent via the injectable route because both products contain identical ingredients. NebuPent and Pentam are FDA approved for different indications.