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Nitrofurantoin Oral Suspension

Last Updated: September 30, 2022
Status: Current

Products Affected - Description
    • Furadantin oral suspension, Casper, 25 mg/5 mL, 230 mL bottle, NDC 70199-0006-32
    • Nitrofurantoin oral suspension, Amneal, 25 mg/5 mL, 230 mL bottle, UPC 65162-0689-88 - discontinued
    • Nitrofurantoin oral suspension, Lupin, 25 mg/5 mL, 230 mL bottle, UPC 43386-0450-11 - discontinued
    • Nitrofurantoin oral suspension, Teva, 25 mg/5 mL, 230 mL bottle, UPC 00472-1992-08
Reason for the Shortage
    • Casper Pharma stated the Furadantin shortage is due to manufacturing delays.
    • Nostrum has nitrofurantoin oral suspension available.
    • Teva did not provide a reason for the shortage.
Available Products
    • Nitrofurantoin oral suspension, Nostrum, 25 mg/5 mL, 240 mL bottle, UPC 70408-0239-32

Estimated Resupply Dates

    • Casper has nitrofurantoin oral suspension available with a short expiration date (December 2022).
    • Teva has nitrofurantoin oral suspension temporarily unavailable and the company cannot estimate a release date.

Alternative Agents & Management

    • Nitrofurantoin 2 mg/mL suspension can be made from nitrofurantoin bulk powder and SyrSpend SF PH4 vehicle. Mix nitrofurantoin with a small amount of suspending vehicle to form a paste. Dilute the paste with additional SyrSpendSF to a final volume of 300 mL. Store at room temperature or under refrigeration in light-resistant bottles. Suspension is stable for 90 days.[1]
    • Macrodantin (nitrofurantoin macrocrystalline) capsules can be opened and mixed with food or water and flushed down a tube.[2]
    • Macrobid (nitrofurantoin monohydrate/macrocrystalline) capsules should not be opened as this may interfere with the nitrofurantoin release mechanism.[2]

References

    1. De Oliveira, FA, Polonini HC, Loures da Silva S, et al., (2017). Stability of Alprazolam, Atropine Sulfate, Glutamine, Levofloxacin, Metoprolol Tartrate, Nitrofurantion, Ondansetron HCl, Oxandrolone, Pregabaline, and Riboflavin in SyrSpend SF PH4 Oral Suspensions. International Journal of Pharmaceutical Compounding, 21(3), 255-263.
    2. Alvogen Customer Service (personal communications). June 5, 2018.

Updated

Updated September 30, 2022 by Leslie Jensen, PharmD, Drug Information Specialist. Created June 5, 2018 by Leslie Jensen, PharmD, Drug Information Specialist. © 2022, Drug Information Service, University of Utah, Salt Lake City, UT.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.