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Methylprednisolone Sodium Succinate Injection Shortage

Last Updated: May 18, 2025
Status: Current

Products Affected - Description
    • Solu-Medrol injection, Pfizer, 125 mg, Act-O-Vial single dose vial, 25 count, NDC 00009-0047-22
    • Solu-Medrol injection, Pfizer, 40 mg, Act-O-Vial single dose vial, 25 count, NDC 00009-0039-28
    • Solu-Medrol injection, Pfizer, 500 mg, single dose vial, 1 count, NDC 00009-0758-01
    • Methylprednisolone Sodium Succinate powder for solution for injection, Fresenius Kabi, 40 mg, single dose vial, 25 count, NDC 63323-0255-03
    • Methylprednisolone Sodium Succinate powder for solution for injection, Hikma, 1 gram, single dose vial, 1 count, NDC 00143-9851-01
    • Methylprednisolone Sodium Succinate powder for solution for injection, Hikma, 125 mg, single dose vial, 25 count, NDC 00143-9754-25
    • Methylprednisolone Sodium Succinate powder for solution for injection, Hikma, 40 mg, single dose vial, 25 count, NDC 00143-9753-25
Reason for the Shortage
    • Pfizer has Solu-Medrol on shortage due to increased demand and manufacturing delays.
    • Fresenius Kabi did not provide a reason for the shortage.
    • Hikma did not provide a reason for the shortage.
Available Products
    • Solu-Medrol injection, Pfizer, 1 gram, single dose vial, 1 count, NDC 00009-0698-01
    • Solu-Medrol injection, Pfizer, 1 gram, Act-O-Vial single dose vial, 1 count, NDC 00009-0018-20
    • Solu-Medrol injection, Pfizer, 2 gram, single dose vial, 1 count, NDC 00009-0850-01
    • Solu-Medrol injection, Pfizer, 500 mg, Act-O-Vial single dose vial, 1 count, NDC 00009-0003-02
    • Methylprednisolone Sodium Succinate powder for solution for injection, Fresenius Kabi, 1 gram, single dose vial, 1 count, NDC 63323-0265-30
    • Methylprednisolone Sodium Succinate powder for solution for injection, Fresenius Kabi, 125 mg, single dose vial, 25 count, NDC 63323-0258-03
    • Methylprednisolone Sodium Succinate powder for solution for injection, Hikma, 500 mg, single dose vial, 1 count, NDC 00143-9850-01

Estimated Resupply Dates

    • Pfizer has Solu-Medrol 125 mg Act-O-Vials available in limited supply. The 500 mg vials are on back order and the company estimates a release date of June 2025. The 40 mg Act-O-Vial are available in limited supply with weekly releases.
    • Hikma has 40 mg vials and 125 mg vials on back order and the company estimates a release date of mid-June 2025 for the 40 mg vials and mid- to late-August 2025 for the 125 mg vials. The 1 gram vials are on allocation.

Updated

Updated May 18, 2025 by Michelle Wheeler, PharmD, Drug Information Specialist. Created March 23, 2023 by Michelle Wheeler, PharmD, Drug Information Specialist. © 2025, Drug Information Service, University of Utah, Salt Lake City, UT.

Further information

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