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Methylprednisolone Acetate Injection Shortage

Last Updated: August 8, 2023
Status: Current

Reason for the Shortage
    • Amneal has methylprednisolone acetate injection available.[1]
    • Eugia has methylprednisolone acetate injection available.[2]
    • Pfizer has Depo-Medrol available. This product was not affected by the tornado in Rocky Mount.[3]
    • Sagent has methylprednisolone acetate injection available.[4]
    • Teva is not currently marketing methylprednisolone acetate.[5]
Available Products
    • Depo-Medrol injection, Pfizer, 20 mg/mL, 5 mL multiple dose vial, 1 count, NDC 00009-0274-01
    • Depo-Medrol injection, Pfizer, 40 mg/mL, 1 mL single dose vial, 1 count, NDC 00009-3073-01
    • Depo-Medrol injection, Pfizer, 40 mg/mL, 1 mL single dose vial, 25 count, NDC 00009-3073-03
    • Depo-Medrol injection, Pfizer, 40 mg/mL, 10 mL multiple dose vial, 1 count, NDC 00009-0280-03
    • Depo-Medrol injection, Pfizer, 40 mg/mL, 10 mL multiple dose vial, 25 count, NDC 00009-0280-52
    • Depo-Medrol injection, Pfizer, 40 mg/mL, 5 mL multiple dose vial, 1 count, NDC 00009-0280-02
    • Depo-Medrol injection, Pfizer, 40 mg/mL, 5 mL multiple dose vial, 25 count, NDC 00009-0280-51
    • Depo-Medrol injection, Pfizer, 80 mg/mL, 1 mL single dose vial, 1 count, NDC 00009-3475-01
    • Depo-Medrol injection, Pfizer, 80 mg/mL, 1 mL single dose vial, 25 count, NDC 00009-3475-03
    • Depo-Medrol injection, Pfizer, 80 mg/mL, 5 mL multiple dose vial, 1 count, NDC 00009-0306-02
    • Depo-Medrol injection, Pfizer, 80 mg/mL, 5 mL multiple dose vial, 25 count, NDC 00009-0306-12
    • Methylprednisolone Acetate injection, Amneal, 40 mg/mL, 1 mL single dose vial, 1 count, NDC 70121-1573-01
    • Methylprednisolone Acetate injection, Amneal, 40 mg/mL, 1 mL single dose vial, 25 count, NDC 70121-1573-05
    • Methylprednisolone Acetate injection, Amneal, 80 mg/mL, 1 mL single dose vial, 1 count, NDC 70121-1574-01
    • Methylprednisolone Acetate injection, Amneal, 80 mg/mL, 1 mL single dose vial, 25 count, NDC 70121-1574-05
    • Methylprednisolone Acetate injection, Eugia US, 40 mg/mL, 10 mL multiple dose vial, 1 count, NDC 55150-0313-01
    • Methylprednisolone Acetate injection, Eugia US, 80 mg/mL, 5 mL multiple dose vial, 1 count, NDC 55150-0314-01
    • Methylprednisolone Acetate injection, Sagent, 40 mg/mL, 10 mL multiple dose vial, 1 count, NDC 25021-0820-10
    • Methylprednisolone Acetate injection, Sagent, 40 mg/mL, 5 mL multiple dose vial, 1 count, NDC 25021-0820-05
    • Methylprednisolone Acetate injection, Sagent, 80 mg/mL, 5 mL multiple dose vial, 1 count, NDC 25021-0821-05

Estimated Resupply Dates

    • All currently marketed presentations are available.

Alternative Agents & Management

    • The table below lists possible alternatives for patients who receive injectable corticosteroid suspensions.
    Table 1. Alternative agents for disorders commonly treated injectable corticosteroid suspensions.6-7
    Intra-articular injections for disorders such as rheumatoid arthritis and bursitis Betamethasone acetate/betamethasone sodium phosphate
    Intralesional injections Triamcinolone acetonide
    <40 mg per treatment

    Methylprednisolone acetate
    20 to 40 mg per treatment for large lesions


References

    1. Amneal (personal communication). August 20, and December 16 and 17, 2021, August 26, 2022; February 23, and July 7, 2023.
    2. Eugia (personal communication. June 28, and August 4, 2023.
    3. Pfizer (personal communication). August 20, September 17, November 19, December 10, 2021, and July 1, August 26, 2022; March 10, April 7, and August 4, 2023.
    4. Sagent (personal communication. July 22, August 26, 2022; March 9, April 6, and August 3, 2023.
    5. Teva (personal communication). August 20, September 17, November 12, December 10, 2021, July 1, August 26, 2022; March 10, and April 7, 2023.
    6. Lexicomp Online. Hudson, OH: Wolters Kluwer Clinical Drug Information, Inc; 2018.
    7. Dexamethasone sodium phosphate injection [package insert]. Lake Zurich, IL: Fresenius Kabi; 2021.

Updated

Updated August 8, 2023 by Michelle Wheeler, PharmD, Drug Information Specialist. Created August 20, 2021 by Stephen Andrews, PharmD, BCPS, CPPS, Drug Information Specialist. © 2023, Drug Information Service, University of Utah, Salt Lake City, UT.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.