Methylprednisolone Acetate Injection
Last Updated: December 21, 2022
Status: Current
Products Affected - Description
-
- Depo-Medrol injection, Pfizer, 20 mg/mL, 5 mL multiple dose vial, 1 count, NDC 00009-0274-01
- Depo-Medrol injection, Pfizer, 40 mg/mL, 5 mL multiple dose vial, 1 count, NDC 00009-0280-02
- Depo-Medrol injection, Pfizer, 40 mg/mL, 5 mL multiple dose vial, 25 count, NDC 00009-0280-51
- Depo-Medrol injection, Pfizer, 80 mg/mL, 1 mL single dose vial, 25 count, NDC 00009-3475-03
- Methylprednisolone Acetate injection, Sagent, 40 mg/mL, 10 mL multiple dose vial, 1 count, NDC 25021-0820-10
- Methylprednisolone Acetate injection, Sagent, 40 mg/mL, 5 mL multiple dose vial, 1 count, NDC 25021-0820-05
- Methylprednisolone Acetate injection, Teva, 40 mg/mL, 1 mL single dose vial, 1 count, NDC 00703-0031-01
- Methylprednisolone Acetate injection, Teva, 40 mg/mL, 1 mL single dose vial, 25 count, NDC 00703-0031-04
- Methylprednisolone Acetate injection, Teva, 40 mg/mL, 10 mL multiple dose vial, 1 count, NDC 00703-0045-01
- Methylprednisolone Acetate injection, Teva, 40 mg/mL, 5 mL multiple dose vial, 1 count, NDC 00703-0043-01
- Methylprednisolone Acetate injection, Teva, 80 mg/mL, 1 mL single dose vial, 1 count, NDC 00703-0051-01
- Methylprednisolone Acetate injection, Teva, 80 mg/mL, 1 mL single dose vial, 25 count, NDC 00703-0051-04
- Methylprednisolone Acetate injection, Teva, 80 mg/mL, 5 mL multiple dose vial, 1 count, NDC 00703-0063-01
Reason for the Shortage
-
- Amneal is actively shipping allocated methylprednisolone acetate single dose vials on historical demand.[1]
- Pfizer has Depo-Medrol on shortage due to increased demand and manufacturing delays.[2]
- Sagent has methylprednisolone acetate injection available.[3]
- Teva did not provide a reason for the shortage.[4]
Available Products
-
- Depo-Medrol injection, Pfizer, 40 mg/mL, 1 mL single dose vial, 1 count, NDC 00009-3073-01
- Depo-Medrol injection, Pfizer, 40 mg/mL, 1 mL single dose vial, 25 count, NDC 00009-3073-03
- Depo-Medrol injection, Pfizer, 40 mg/mL, 10 mL multiple dose vial, 1 count, NDC 00009-0280-03
- Depo-Medrol injection, Pfizer, 40 mg/mL, 10 mL multiple dose vial, 25 count, NDC 00009-0280-52
- Depo-Medrol injection, Pfizer, 80 mg/mL, 1 mL single dose vial, 1 count, NDC 00009-3475-01
- Depo-Medrol injection, Pfizer, 80 mg/mL, 5 mL multiple dose vial, 1 count, NDC 00009-0306-02
- Depo-Medrol injection, Pfizer, 80 mg/mL, 5 mL multiple dose vial, 25 count, NDC 00009-0306-12
- Methylprednisolone Acetate injection, Amneal, 40 mg/mL, 1 mL single dose vial, 1 count, NDC 70121-1573-01
- Methylprednisolone Acetate injection, Amneal, 40 mg/mL, 1 mL single dose vial, 25 count, NDC 70121-1573-05
- Methylprednisolone Acetate injection, Amneal, 80 mg/mL, 1 mL single dose vial, 1 count, NDC 70121-1574-01
- Methylprednisolone Acetate injection, Amneal, 80 mg/mL, 1 mL single dose vial, 25 count, NDC 70121-1574-05
- Methylprednisolone Acetate injection, Sagent, 80 mg/mL, 5 mL multiple dose vial, 1 count, NDC 25021-0821-05
Estimated Resupply Dates
-
- Sagent has methylprednisolone acetate 40 mg/mL 1 mL and 5 mL vials on allocation.
- Teva has all presentations of methylprednisolone acetate on back order and the company cannot estimate a release date.
- Pfizer has Depo-Medrol 20 mg/mL 5 mL vials in 1 count on back order and the company estimates a release date of December 2022. The 40 mg/mL 5 mL vials in 1 count and 25 count are on back order with an estimated release date of January 2023 for the 1 count and December 2022 for the 25 count. The 80 mg/mL 1 mL vials in 25 count are available in limited supply.
Alternative Agents & Management
-
- The table below lists possible alternatives for patients who receive injectable corticosteroid suspensions.
Table 1. Alternative agents for disorders commonly treated injectable corticosteroid suspensions.5-6 Intra-articular injections for disorders such as rheumatoid arthritis and bursitis Betamethasone acetate/betamethasone sodium phosphate Intralesional injections Triamcinolone acetonide
<40 mg per treatment
Methylprednisolone acetate
20 to 40 mg per treatment for large lesions
References
-
- Amneal (personal communication). August 20, and December 16 and 17, 2021, and August 26, 2022.
- Pfizer (personal communication). August 20, September 17, November 19, December 10, 2021, and July 1 and August 26, 2022.
- Sagent (personal communication. July 22 and August 26, 2022.
- Teva (personal communication). August 20, September 17, November 12, December 10, 2021, and July 1 and August 26, 2022.
- Lexicomp Online. Hudson, OH: Wolters Kluwer Clinical Drug Information, Inc; 2018.
- Dexamethasone sodium phosphate injection [package insert]. Lake Zurich, IL: Fresenius Kabi; 2021.
Updated
Updated December 21, 2022 by Michelle Wheeler, PharmD, Drug Information Specialist. Created August 20, 2021 by Stephen Andrews, PharmD, BCPS, CPPS, Drug Information Specialist. © 2022, Drug Information Service, University of Utah, Salt Lake City, UT.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.