Skip to main content

Methylprednisolone Acetate Injection Shortage

Last Updated: August 25, 2025
Status: Current

Products Affected - Description
    • Depo-Medrol injection, Pfizer, 40 mg/mL, 1 mL single dose vial, 25 count, NDC 00009-3073-03
    • Depo-Medrol injection, Pfizer, 40 mg/mL, 5 mL multiple dose vial, 1 count, NDC 00009-0280-02
    • Depo-Medrol injection, Pfizer, 40 mg/mL, 5 mL multiple dose vial, 25 count, NDC 00009-0280-51
    • Depo-Medrol injection, Pfizer, 80 mg/mL, 1 mL single dose vial, 25 count, NDC 00009-3475-03
    • Depo-Medrol injection, Pfizer, 80 mg/mL, 5 mL multiple dose vial, 1 count, NDC 00009-0306-02
    • Depo-Medrol injection, Pfizer, 80 mg/mL, 5 mL multiple dose vial, 25 count, NDC 00009-0306-12
    • Methylprednisolone Acetate injection, Eugia US, 40 mg/mL, 10 mL multiple dose vial, 1 count, NDC 55150-0313-01
    • Methylprednisolone Acetate injection, Sandoz, 40 mg/mL, 10 mL vial, 1 count, NDC 00781-3522-70
    • Methylprednisolone Acetate injection, Sandoz, 40 mg/mL, 5 mL vial, 1 count, NDC 00781-3522-75
    • Methylprednisolone Acetate injection, Sandoz, 80 mg/mL, 5 mL vial, 1 count, NDC 00781-3516-75
Reason for the Shortage
    • Amneal has methylprednisolone acetate injection available.
    • Eugia did not provide a reason for the shortage.
    • Pfizer has methylprednisolone acetate injection on shortage due to manufacturing delays and increased demand.
    • Sagent has methylprednisolone acetate injection available.
    • Sandoz did not provide a reason for the shortage.
    • Teva discontinued methylprednisolone acetate injection in July 2023.
Available Products
    • Depo-Medrol injection, Pfizer, 20 mg/mL, 5 mL multiple dose vial, 1 count, NDC 00009-0274-01
    • Depo-Medrol injection, Pfizer, 40 mg/mL, 1 mL single dose vial, 1 count, NDC 00009-3073-01
    • Depo-Medrol injection, Pfizer, 40 mg/mL, 10 mL multiple dose vial, 1 count, NDC 00009-0280-03
    • Depo-Medrol injection, Pfizer, 40 mg/mL, 10 mL multiple dose vial, 25 count, NDC 00009-0280-52
    • Depo-Medrol injection, Pfizer, 80 mg/mL, 1 mL single dose vial, 1 count, NDC 00009-3475-01
    • Methylprednisolone Acetate injection, Amneal, 40 mg/mL, 1 mL single dose vial, 1 count, NDC 70121-1573-01
    • Methylprednisolone Acetate injection, Amneal, 40 mg/mL, 1 mL single dose vial, 25 count, NDC 70121-1573-05
    • Methylprednisolone Acetate injection, Amneal, 80 mg/mL, 1 mL single dose vial, 1 count, NDC 70121-1574-01
    • Methylprednisolone Acetate injection, Amneal, 80 mg/mL, 1 mL single dose vial, 25 count, NDC 70121-1574-05
    • Methylprednisolone Acetate injection, Amneal, 80 mg/mL, 5 mL single dose vial, 1 count, NDC 70121-1610-01
    • Methylprednisolone Acetate injection, Amneal, 80 mg/mL, 5 mL single dose vial, 25 count, NDC 70121-1610-05
    • Methylprednisolone Acetate injection, Sagent, 40 mg/mL, 10 mL multiple dose vial, 1 count, NDC 25021-0820-10
    • Methylprednisolone Acetate injection, Sagent, 40 mg/mL, 5 mL multiple dose vial, 1 count, NDC 25021-0820-05
    • Methylprednisolone Acetate injection, Sagent, 80 mg/mL, 5 mL multiple dose vial, 1 count, NDC 25021-0821-05

Estimated Resupply Dates

    • Eugia has methylprednisolone acetate 40 mg/mL 10 mL vials on back order and the company cannot estimate a release date.
    • Sandoz has methylprednisolone acetate 40 mg/mL 5 mL and 10 mL vials and 80 mg/mL 5 mL vials on back order and the company cannot estimate a release date.
    • Pfizer has Depo-Medrol 40 mg/mL 1 mL vials in 25 count and 40 mg/mL 5 mL vials in 25 count on back order and the company estimates a release date of September 2025. The 80 mg/mL 1 mL vials in 25 count are on back order and the company estimates a release date of November 2025. The 80 mg/mL 5 mL vials in 1 count and 25 count are on back order and the company estimates a release date of October 2025. The 40 mg/mL 1 mL vials in 1 count are available in limited supply.

Updated

Created August 25, 2025 by Michelle Wheeler, PharmD, Drug Information Specialist. © 2025, Drug Information Service, University of Utah, Salt Lake City, UT.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.