Leucovorin Calcium Injection Shortage
Last Updated: April 21, 2025
Status: Current
Products Affected - Description
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- Leucovorin Calcium injection, Fresenius Kabi, 10 mg/mL, 50 mL vial, 1 count, NDC 63323-0631-50
- Leucovorin Calcium lyophilized powder for injection, Hikma, 50 mg, vial, 1 count, NDC 00143-9555-01
- Leucovorin Calcium lyophilized powder for solution for injection, Hikma, 350 mg, vial, 1 count, NDC 00143-9552-01
- Leucovorin Calcium lyophilized powder for injection, Sagent, 200 mg, vial, 1 count, NDC 25021-0815-30
- Leucovorin Calcium lyophilized powder for injection, Sagent, 500 mg, vial, 1 count, NDC 25021-0828-50
Reason for the Shortage
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- Fresenius Kabi had leucovorin on shortage due to manufacturing delays and increased demand.
- Hikma has leucovorin on shortage due to increased demand.
- Meitheal has leucovorin injection available.
- Sagent has leucovorin on shortage due to increased demand.
- Teva has discontinued leucovorin injection.
- Viatris had leucovorin injection available.
- Slate Run Pharmaceuticals has leucovorin injection available.
Available Products
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- Leucovorin Calcium injection, Fresenius Kabi, 10 mg/mL, 10 mL vial, 1 count, NDC 63323-0631-10
- Leucovorin Calcium lyophilized powder for solution for injection, Fresenius Kabi, 500 mg, vial, 1 count, NDC 63323-0711-00
- Leucovorin Calcium, Fresenius Kabi, 200 mg, vial, 1 count, NDC 63323-0710-50
- Leucovorin Calcium lyophilized powder for injection, Hikma, 100 mg, vial, 1 count, NDC 00143-9554-01
- Leucovorin Calcium lyophilized powder for injection, Hikma, 200 mg, vial, 1 count, NDC 00143-9553-01
- Leucovorin Calcium, Meitheal Pharmaceuticals, 100 mg, vial, 1 count, NDC 71288-0161-20
- Leucovorin Calcium, Meitheal Pharmaceuticals, 200 mg, vial, 1 count, NDC 71288-0162-30
- Leucovorin Calcium, Meitheal Pharmaceuticals, 350 mg, vial, 1 count, NDC 71288-0163-30
- Leucovorin Calcium, Meitheal Pharmaceuticals, 50 mg, vial, 1 count, NDC 71288-0160-10
- Leucovorin Calcium, Meitheal Pharmaceuticals, 500 mg, vial, 1 count, NDC 71288-0164-50
- Leucovorin Calcium lyophilized powder for injection, Mylan Institutional (Viatris), 200 mg, vial, 1 count, NDC 67457-0529-20
- Leucovorin Calcium lyophilized powder for injection, Mylan Institutional (Viatris), 350 mg, vial, 1 count, NDC 67457-0530-35
- Leucovorin Calcium lyophilized powder for injection, Mylan Institutional (Viatris), 50 mg, vial, 1 count, NDC 67457-0528-10
- Leucovorin Calcium lyophilized powder for injection, Sagent, 100 mg, vial, 10 count, NDC 25021-0814-30
- Leucovorin Calcium lyophilized powder for injection, Sagent, 350 mg, vial, 1 count, NDC 25021-0816-30
- Leucovorin Calcium lyophilized powder for solution for injection, Sagent, 50 mg, vial, 10 count, NDC 25021-0813-10
- Leucovorin Calcium, Slate Run Pharmaceuticals, 100 mg, vial, 1 count, NDC 70436-0117-80
- Leucovorin Calcium, Slate Run Pharmaceuticals, 200 mg, vial, 1 count, NDC 70436-0118-80
- Leucovorin Calcium, Slate Run Pharmaceuticals, 350 mg, vial, 1 count, NDC 70436-0119-80
- Leucovorin Calcium, Slate Run Pharmaceuticals, 50 mg, vial, 10 count, NDC 70436-0116-82
- Leucovorin Calcium, Slate Run Pharmaceuticals, 500 mg, vial, 1 count, NDC 70436-0120-80
Estimated Resupply Dates
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- Fresenius Kabi has leucovorin 10 mg/mL 50 mL vials on back order and the company estimates a release date of early-May 2025.
- Hikma has leucovorin 350 mg vials on allocation. There are short-dated 50 mg vials available with an expiration date of < October 2025.
- Sagent has leucovorin 200 mg vials on a limited allocation. The 500 mg vials are on back order and the company cannot estimate a release date.
Updated
Updated April 21, 2025 by Michelle Wheeler, PharmD, Drug Information Specialist. Created June 6, 2010 by Jane Chandramouli, PharmD, Drug Information Specialist. © 2025, Drug Information Service, University of Utah, Salt Lake City, UT.
Further information
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