Skip to main content

Leucovorin Calcium Injection

Last Updated: January 10, 2023
Status: Current

Products Affected - Description
    • Leucovorin Calcium injection, Fresenius Kabi, 10 mg/mL, 50 mL vial, 1 count, NDC 63323-0631-50
    • Leucovorin Calcium, Fresenius Kabi, 200 mg, vial, 1 count, NDC 63323-0710-50
    • Leucovorin Calcium lyophilized powder for injection, Hikma, 100 mg, vial, 1 count, NDC 00143-9554-01
    • Leucovorin Calcium lyophilized powder for injection, Hikma, 200 mg, vial, 1 count, NDC 00143-9553-01
    • Leucovorin Calcium lyophilized powder for solution for injection, Hikma, 350 mg, vial, 1 count, NDC 00143-9552-01
    • Leucovorin Calcium lyophilized powder for injection, Mylan Institutional (Viatris), 350 mg, vial, 1 count, NDC 67457-0530-35
    • Leucovorin Calcium lyophilized powder for injection, Mylan Institutional (Viatris), 50 mg, vial, 1 count, NDC 67457-0528-10
    • Leucovorin Calcium lyophilized powder for injection, Sagent, 100 mg, vial, 10 count, NDC 25021-0814-30
    • Leucovorin Calcium lyophilized powder for injection, Sagent, 200 mg, vial, 1 count, NDC 25021-0815-30
    • Leucovorin Calcium lyophilized powder for injection, Sagent, 350 mg, vial, 1 count, NDC 25021-0816-30
    • Leucovorin Calcium lyophilized powder for injection, Sagent, 500 mg, vial, 1 count, NDC 25021-0828-50
    • Leucovorin Calcium lyophilized powder for solution for injection, Sagent, 50 mg, vial, 10 count, NDC 25021-0813-10
    • Leucovorin Calcium, Teva, 100 mg, vial, 1 count, NDC 00703-5140-01 - discontinued
    • Leucovorin Calcium, Teva, 350 mg, vial, 1 count, NDC 00703-5145-01 - discontinued
Reason for the Shortage
    • Fresenius Kabi had leucovorin on shortage due to manufacturing delays and increased demand.
    • Hikma has leucovorin on shortage due to increased demand.
    • Mylan Institutional has leucovorin on shortage due to increased demand.
    • Sagent has leucovorin on shortage due to manufacturing delays.
    • Teva has discontinued leucovorin injection.
Available Products
    • Leucovorin Calcium injection, Fresenius Kabi, 10 mg/mL, 10 mL vial, 1 count, NDC 63323-0631-10
    • Leucovorin Calcium lyophilized powder for solution for injection, Fresenius Kabi, 500 mg, vial, 1 count, NDC 63323-0711-00
    • Leucovorin Calcium lyophilized powder for injection, Hikma, 50 mg, vial, 1 count, NDC 00143-9555-01
    • Leucovorin Calcium lyophilized powder for injection, Mylan Institutional (Viatris), 200 mg, vial, 1 count, NDC 67457-0529-20

Estimated Resupply Dates

    • Fresenius Kabi has leucovorin 200 mg vials on back order and the company estimates a release date of mid-January 2023. The 10 mg/mL 50 mL vials are on back order and the company estimates a release date of early-February 2023.
    • Hikma has leucovorin 350 mg vials on allocation. The 100 mg and 200 mg vials are on back order and the company estimates a release date of early- to mid-February 2023 for the 100 mg vials and early-February 2023 for the 200 mg vials.
    • Sagent has leucovorin 200 mg, 350 mg, and 500 mg vials on a limited allocation. The 100 mg vials are on back order and the company estimates a release date of January 2023. There are short-dated 50 mg vials with an expiration date of January 2023.

Updated

Updated January 10, 2023 by Michelle Wheeler, PharmD, Drug Information Specialist. Created June 6, 2010 by Jane Chandramouli, PharmD, Drug Information Specialist. © 2023, Drug Information Service, University of Utah, Salt Lake City, UT.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.