Iopamidol Injection

• • Isovue Multipack-250 solution for injection, Bracco Diagnostics, 51%, 200 mL bulk glass bottle, 10 count, NDC 00270-1317-41 - discontinued
  • Isovue Multipack-300 solution for injection, Bracco Diagnostics, 61%, 200 mL pharmacy bulk glass bottle, 10 count, NDC 00270-1315-41 - discontinued
  • Isovue Multipack-300 solution for injection, Bracco Diagnostics, 61%, 500 mL pharmacy bulk glass bottle, 6 count, NDC 00270-1315-98 - discontinued
  • Isovue Multipack-370 solution for injection, Bracco Diagnostics, 76%, 200 mL pharmacy bulk glass bottle, 10 count, NDC 00270-1316-41 - discontinued
  • Isovue Multipack-370 solution for injection, Bracco Diagnostics, 76%, 500 mL pharmacy bulk glass bottle, 6 count, NDC 00270-1316-98 - discontinued
  • Isovue-200 solution for injection, Bracco Diagnostics, 41%, 200 mL single dose glass bottle, 10 count, NDC 00270-1314-15
  • Isovue-200 solution for injection, Bracco Diagnostics, 41%, 50 mL single dose vial, 10 count, NDC 00270-1314-30 - discontinued
  • Isovue-250 solution for injection, Bracco Diagnostics, 51%, 100 mL single dose glass bottle, 10 count, NDC 00270-1317-02
  • Isovue-250 solution for injection, Bracco Diagnostics, 51%, 150 mL single dose glass bottle, 10 count, NDC 00270-1317-09 - discontinued
  • Isovue-250 solution for injection, Bracco Diagnostics, 51%, 50 mL single dose vial, 10 count, NDC 00270-1317-05 - discontinued
  • Isovue-300 solution for injection, Bracco Diagnostics, 61%, 100 mL single dose glass bottle, 10 count, NDC 00270-1315-35
  • Isovue-300 solution for injection, Bracco Diagnostics, 61%, 200 mL imaging bulk package glass bottle, 10 count, NDC 00270-1315-45
  • Isovue-300 solution for injection, Bracco Diagnostics, 61%, 30 mL single dose vial, 10 count, NDC 00270-1315-25
  • Isovue-300 solution for injection, Bracco Diagnostics, 61%, 50 mL single dose vial, 10 count, NDC 00270-1315-30 - discontinued
  • Isovue-300 solution for injection, Bracco Diagnostics, 61%, 500 mL imaging bulk package glass bottle, 6 count, NDC 00270-1315-95
  • Isovue-300 solution for injection, Bracco Diagnostics, 61%, 75 mL single dose glass bottle, 10 count, NDC 00270-1315-47 - discontinued
  • Isovue-370 solution for injection, Bracco Diagnostics, 76%, 100 mL single dose glass bottle, 10 count, NDC 00270-1316-35
  • Isovue-370 solution for injection, Bracco Diagnostics, 76%, 125 mL single dose glass bottle, 10 count, NDC 00270-1316-04 - discontinued
  • Isovue-370 solution for injection, Bracco Diagnostics, 76%, 150 mL single dose glass bottle, 10 count, NDC 00270-1316-37 - discontinued
  • Isovue-370 solution for injection, Bracco Diagnostics, 76%, 200 mL imaging bulk package glass bottle, 10 count, NDC 00270-1316-45
  • Isovue-370 solution for injection, Bracco Diagnostics, 76%, 50 mL single dose vial, 10 count, NDC 00270-1316-30 - discontinued
  • Isovue-370 solution for injection, Bracco Diagnostics, 76%, 500 mL imaging bulk package glass bottle, 6 count, NDC 00270-1316-95
  • Isovue-370 solution for injection, Bracco Diagnostics, 76%, 75 mL single dose glass bottle, 10 count, NDC 00270-1316-52 - discontinued
  • Isovue-M 200 intrathecal solution for injection, Bracco Diagnostics, 41%, 10 mL single dose vial, 10 count, NDC 00270-1411-11
  • Isovue-M 200 intrathecal solution for injection, Bracco Diagnostics, 41%, 20 mL single dose vial, 10 count, NDC 00270-1411-25 - discontinued
  • Isovue-M 300 intrathecal solution for injection, Bracco Diagnostics, 61%, 15 mL single dose vial, 10 count, NDC 00270-1412-15

• • Iohexol (Omnipaque - GE Healthcare) injection is currently in shortage due to the shutdown of a production facility in Shanghai, China during a COVID-19 lockdown. The facility is open again and production is operating at full capacity. As a result of the iohexol shortage, other contrast agents may be affected as organizations seek suitable alternatives. https://www.ge.com/news/press-releases/ge-healthcare-update-on-iodinated-contrast-media
  • Bracco has Isovue on shortage due to increased demand. Bracco is taking measures to protect Isovue inventory for customers during the current situation.
  • Bracco discontinued Isovue-M 200 (41%) in 20 mL vials in April 2022. Isovue 370 (76%) in 150 mL bottles were discontinued in November 2022.

• • There is insufficient supply for usual ordering

Estimated Resupply Dates

• • Bracco has all presentations on allocation to existing customers.

Alternative Agents & Management

• • More information can be found at Considerations for Imaging Contrast Shortage Management and Conservation
  • The American College of Radiology (ACR) has issued a statement addressing the shortage of iodinated contrast media. https://www.acr.org/Advocacy-and-Economics/ACR-Position-Statements/Contrast-Media-Shortage