Hypromellose Ophthalmic Solution

• • Gonak, Akorn, 2.5%, 15 mL NDC 17478-0064-12
  • Goniosoft, OCuSOFT, 2.5%, 15 mL NDC 54799-0503-15
  • Goniotaire, Altaire, 2.5%, 15 mL NDC 59390-0182-13

• • Akorn has Gonak on shortage due to lack of raw materials.1
  • HUB Pharmaceuticals is planning on relaunching Goniovisc in late-2020.2
  • Altaire has Goniotaire on shortage due to a voluntary recall.[3]
  • OcuSoft did not provide a reason for the shortage.[4]

• • There is insufficient supply for usual ordering

Estimated Resupply Dates

• • Akorn has Gonak 2.5% ophthalmic solution 15 mL bottles on allocation.1
  • Altaire has Goniotaire 2.5% ophthalmic solution 15 mL bottles on back order and the company cannot estimate a release date.[3]
  • Hub Pharmaceuticals has Goniovisc on long-term back order and the company estimates a relaunch date of early-2021.[2]
  • OCuSOFT has Goniosoft 2.5% ophthalmic solution on back order and the company cannot estimate a release date.4

Alternative Agents & Management

• • Hypromellose-containing products are used in ocular examinations and to treat dry eye.[5] There are products available ranging from hypromellose 0.2% to 2.5%.[5] The American Academy of Ophthalmology does not recommend a specific product over another.[6] Use products without preservatives if applying more than 4 times daily.[6]

References

• 1. Akorn (personal communication). June 8, July 13, September 7, October 25, December 13 and 26, 2018; March 1, May 8, July 29, September 17, December 18, 2019; January 30, and April 27, 2020.
  2. HUB Pharmaceuticals (personal communication). June 8, July 11, September 5, October 25, December 13, 2018; May 8, July 29, September 13, October 2, December 18, 2019; January 28, and April 27, 2020.
  3. Altaire Pharmaceuticals (personal communication). June 8, July 11, September 5, October 25, December 13, 2018; May 8 and 22, September 17, and December 18, 2019.
  4. Ocusoft/Cynacon (personal communication). June 8, July 11, September 5, October 25, December 13, 2018; May 8, July 29, September 17, and December 18, 2019.
  5. Lexi-Drugs Online. Hudson, OH: Lexi-Comp, Inc; 2018.
  6. American Academy of Ophthalmology Cornea/External Disease Panel. Preferred Practice Patern Guidelines. Dry Eye Syndrome. American Academy of Ophthalmology website. www.aao.org/ppp. 2013. Accessed June 11, 2018.