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Hypromellose Ophthalmic Solution Shortage

Last Updated: May 21, 2025
Status: Current

Products Affected - Description
    • Goniotaire, Altaire, 2.5%, 15 mL NDC 59390-0182-13
Reason for the Shortage
    • Akorn ceased operations in February 2023.1
    • Altaire has Goniotaire on shortage due to a voluntary recall.[2]
    • Hub has Vista Gonio available.[3]
Available Products
    • Vista Gonio, Hub Pharmaceuticals, 2.5%, 15 mL 1 count, NDC 77790-0022-15

Estimated Resupply Dates

    • Altaire has Goniotaire 2.5% ophthalmic solution in 15 mL bottles on back order and the company cannot estimate a release date.[2]

Alternative Agents & Management

    • Hypromellose-containing products are used in ocular examinations and to treat dry eye.[4] There are products available ranging from hypromellose 0.2% to 2.5%.[4] The American Academy of Ophthalmology does not recommend a specific product over another.[5] Use products without preservatives if applying more than 4 times daily.[5]

References

    1. Akorn (personal communication). June 8, July 13, September 7, October 25, December 13 and 26, 2018; March 1, May 8, July 29, September 17, December 18, 2019; January 30, April 27, June 30, and September 9 and 30, 2020; January 12, April 7, May 14, June 30, July 21, August 26, October 7, December 22, 2021; March 30, June 16, August 26, November 21, 2022; and February 22, 2023.
    2. Altaire Pharmaceuticals (personal communication). June 8, July 11, September 5, October 25, December 13, 2018; May 8 and 22, September 17, and December 18, 2019; September 10, 2020; January 12, April 5, July 1, August 26, December 22, 2021; March 31, June 16, August 26, November 21, 2022, January 12, April 26, July 14, September 18, 2023; March 22, August 22, and December 27, 2024; April 1 and May 20, 2025.
    3. Hub (personal communication). November 27, 2023; January 23, April 23, August 16, and December 29, 2024; April 1, 2025.
    4. Lexi-Drugs Online. Hudson, OH: Lexi-Comp, Inc; 2018.
    5. American Academy of Ophthalmology Cornea/External Disease Panel. Preferred Practice Patern Guidelines. Dry Eye Syndrome. American Academy of Ophthalmology website. www.aao.org/ppp. 2013. Accessed June 11, 2018.

Updated

Updated May 21, 2025 by Leslie Jensen, PharmD, Drug Information Specialist. Created June 8, 2018 by Anthony Trovato, PharmD, BCPS. © 2025, Drug Information Service, University of Utah, Salt Lake City, UT.

Further information

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