Skip to Content

Dorzolamide 2% and Timolol 0.5% Ophthalmic Solution

Last Updated: April 20, 2018
Status: Current

Dorzolamide 2% and Timolol 0.5% Ophthalmic Solution

Products Affected - Description
    • Cosopt ophthalmic solution, Akorn, 22.3 mg-6.8 mg/mL, 10 mL Ocumeter Plus bottle, 1 count, NDC 17478-0605-10
    • Dorzolamide and Timolol ophthalmic solution, Akorn, 22.3 mg-6.8 mg/mL, 10 mL bottle, 1 count, NDC 50383-0233-10
    • Dorzolamide and Timolol ophthalmic solution, Sandoz, 22.3 mg-6.8 mg/mL, 10 mL bottle, 1 count, NDC 61314-0030-02
    • Dorzolamide and Timolol ophthalmic solution, Teva, 22.3 mg-6.8 mg/mL, 10 mL bottle, 1 count, NDC 00591-2482-79
    • Dorzolamide and Timolol ophthalmic solution, Valeant, 22.3 mg-6.8 mg/mL, 10 mL bottle, 1 count, NDC 24208-0486-10
Reason for the Shortage
    • Akorn has dorzolamide and timolol ophthalmic solution on shortage due to manufacturing delays.
    • Sandoz did not provide a reason for the shortage.
    • Teva discontinued dorzolamide and timolol ophthalmic solution in April 2018.
    • Valeant did not provide a reason for the shortage.
Available Products
    • Cosopt PF ophthalmic solution, Akorn, 22.3 mg-6.8 mg/mL, 0.2 mL single-use preservative-free vial, 60 count, NDC 17478-0604-30

Estimated Resupply Dates

    • Akorn has dorzolamide 2% and timolol 0.5% ophthalmic solution in 10 mL bottles on allocation. The company has Cosopt 2%/0.5% ophthalmic solution in 10 mL bottles on back order and the company cannot estimate a release date.
    • Sandoz has dorzolamide 2% and timolol 0.5% ophthalmic solution in 10 mL bottles on back order and the company estimates a release date of late-April 2018.
    • Valeant has dorzolamide 2% and timolol 0.5% ophthalmic solution in 10 mL bottles on back order and the company estimates a release date of late-May 2018.

Implications for Patient Care

    • Each product contains dorzolamide hydrochloride 22.3 mg/mL (equivalent to dorzolamide 2%) and timolol maleate 6.8 mg/mL (equivalent to timolol 0.5%).

Updated

Updated April 20, 2018 by Michelle Wheeler, PharmD, Drug Information Specialist. Created October 30, 2017 by Benjamin Witt, PharmD, BCPS, Drug Information Specialist. Copyright 2018, Drug Information Service, University of Utah, Salt Lake City, UT.

Hide