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Bupivacaine with Epinephrine Injection

Last Updated: January 23, 2023
Status: Current

Products Affected - Description
    • Bupivacaine (with epinephrine 1:200,000) injection, Pfizer, 0.25%, 10 mL vial, 50 count, NDC 00409-9042-01
    • Bupivacaine (with epinephrine 1:200,000) injection, Pfizer, 0.25%, 30 mL vial, 100 count, NDC 00409-9042-17
    • Bupivacaine (with epinephrine 1:200,000) injection, Pfizer, 0.25%, 50 mL vial, 25 count, NDC 00409-9043-01
    • Bupivacaine (with epinephrine 1:200,000) injection, Pfizer, 0.5%, 10 mL vial, 50 count, NDC 00409-9045-01
    • Bupivacaine (with epinephrine 1:200,000) injection, Pfizer, 0.5%, 30 mL vial, 100 count, NDC 00409-9045-17
    • Bupivacaine (with epinephrine 1:200,000) injection, Pfizer, 0.5%, 50 mL vial, 25 count, NDC 00409-9046-01
    • Marcaine (with epinephrine 1:200,000) injection, Pfizer, 0.25%, 10 mL vial, 10 count, NDC 00409-1746-10
    • Marcaine (with epinephrine 1:200,000) injection, Pfizer, 0.25%, 30 mL vial, 10 count, NDC 00409-1746-30
    • Marcaine (with epinephrine 1:200,000) injection, Pfizer, 0.25%, 50 mL vial, 1 count, NDC 00409-1752-50
    • Marcaine (with epinephrine 1:200,000) injection, Pfizer, 0.5%, 10 mL vial, 10 count, NDC 00409-1749-10
    • Marcaine (with epinephrine 1:200,000) injection, Pfizer, 0.5%, 30 mL vial, 10 count, NDC 00409-1749-29
    • Marcaine (with epinephrine 1:200,000) injection, Pfizer, 0.5%, 50 mL vial, 1 count, NDC 00409-1755-50
    • Sensorcaine (with epinephrine 1:200,000) injection, Fresenius Kabi, 0.25%, 50 mL vial, 25 count, NDC 63323-0461-57
    • Sensorcaine (with epinephrine 1:200,000) injection, Fresenius Kabi, 0.5%, 50 mL vial, 25 count, NDC 63323-0463-57
    • Sensorcaine-MPF (with epinephrine 1:200,000) injection, Fresenius Kabi, 0.25%, 10 mL vial, 25 count, NDC 63323-0468-17
    • Sensorcaine-MPF (with epinephrine 1:200,000) injection, Fresenius Kabi, 0.25%, 30 mL vial, 25 count, NDC 63323-0468-37
    • Sensorcaine-MPF (with epinephrine 1:200,000) injection, Fresenius Kabi, 0.5%, 10 mL vial, 25 count, NDC 63323-0462-17
    • Sensorcaine-MPF (with epinephrine 1:200,000) injection, Fresenius Kabi, 0.5%, 30 mL sterile pack vial, 5 count, NDC 63323-0462-31
    • Sensorcaine-MPF (with epinephrine 1:200,000) injection, Fresenius Kabi, 0.5%, 30 mL vial, 25 count, NDC 63323-0462-37
    • Sensorcaine-MPF (with epinephrine 1:200,000) injection, Fresenius Kabi, 0.75%, 30 mL vial, 25 count, NDC 63323-0460-37
Reason for the Shortage
    • Fresenius Kabi has bupivacaine and epinephrine on shortage due to increased demand and manufacturing delays.
    • Pfizer has bupivacaine with epinephrine on shortage due to manufacturing delays.
Available Products
    • There are no presentations available

Estimated Resupply Dates

    • Fresenius Kabi has 0.25% Sensorcaine-MPF with epinephrine 10 mL and 30 mL vials on back order and the company estimates a release date of late-February 2023. The 0.25% Sensorcaine with epinephrine 50 mL vials are on back order and the company estimates a release date of late-February 2023. The 0.5% Sensorcaine-MPF with epinephrine 10 mL and 30 mL vials are on back order and the company estimates a release date of late-February 2023. The 0.5% Sensorcaine with epinephrine 50 mL vials are on back order and the company estimates a release date of late-February 2023. The 0.5% Sensorcaine-MPF with epinephrine 30 mL sterile packs are on back order and the company cannot estimate a release date. The 0.75% Sensorcaine-MPF with epinephrine 30 mL vials are on back order and the company cannot estimate a release date.
    • Pfizer has 0.25% bupivacaine with epinephrine 10 mL and 30 mL preservative-free vials on back order and the company estimates a release date of February 2024. The 0.25% bupivacaine with epinephrine 50 mL vials are on back order and the company estimates a release date of February 2024. The 0.5% bupivacaine with epinephrine 10 mL and 30 mL preservative-free vials are on back order and the company estimates a release date of February 2024. The 0.5% bupivacaine with epinephrine 50 mL vials are on back order and the company estimates a release date of February 2024.
    • Pfizer has 0.25% Marcaine with epinephrine 10 mL and 30 mL vials on back order and the company estimates a release date of August 2023. The 0.25% Marcaine with epinephrine 50 mL vials are on back order and the company estimates a release date of January 2023. The 0.5% Marcaine with epinephrine 10 mL and 30 mL vials are on back order and the company estimates a release date of April 2023 for the 10 mL vials and September 2023 for the 30 mL vials. The 0.5% Marcaine with epinephrine 50 mL vials are on back order and the company estimates a release date of January 2023. All Marcaine with epinephrine presentations are only available via direct orders.

Updated

Updated January 23, 2023 by Michelle Wheeler, PharmD, Drug Information Specialist. Created September 2, 2016 by Michelle Wheeler, PharmD, Drug Information Specialist. © 2023, Drug Information Service, University of Utah, Salt Lake City, UT.

Further information

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