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Asparaginase Erwinia chrysanthemi

Last Updated: January 11, 2023
Status: Current

Products Affected - Description
    • Erwinaze lyophilized powder for injection, Clinigen, 10,000 unit, vial, 1 count, NDC 57902-0249-01
    • Erwinaze lyophilized powder for injection, Clinigen, 10,000 unit, vial, 5 count, NDC 57902-0249-05
Reason for the Shortage
    • Erwinaze supply disruption is due to ongoing manufacturing issues and capacity constraints at Porton Biopharma Limited (PBL), the sole manufacturer of Erwinaze.
    • Jazz Pharmaceuticals recommends checking your wholesaler for Rylaze availability.
Available Products
    • There are no presentations available

Estimated Resupply Dates

    • Clinigen is not currently supplying Erwinaze and the company cannot estimate when product will be available again.

Implications for Patient Care

    • As of mid-December 2021, Clinigen is no longer providing Erwinase for personal importation

Alternative Agents & Management

    • Jazz has Rylaze (asparaginase erwinia chrysanthemi (recombinant)-rywn) available to order through specialty distributors.

Updated

Updated January 11, 2023 by Leslie Jensen, PharmD, Drug Information Specialist. Created October 11, 2018 by Michelle Wheeler, PharmD, Drug Information Specialist. © 2023, Drug Information Service, University of Utah, Salt Lake City, UT.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.