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Asparaginase Erwinia chrysanthemi Shortage

Last Updated: June 20, 2018
Status: Resolved

Reason for the Shortage
    • Jazz has Erwinaze available.
Available Products
    • Erwinaze, Jazz Pharmaceuticals, 10,000 unit, 3 mL vial, 5 count, NDC 57902-0249-05

Estimated Resupply Dates

    • Jazz Pharmaceuticals has Erwinaze available.


    • Jazz Pharmaceuticals sent Dear Health Care Provider letters regarding the administration of certain batches of Erwinaze (Batches 174K, 177K, 178K, 179K, 180K, 181K, 182K, 183K, 184K, 185ak, 186). Particulate matter was seen in vials from these batches during routine inspections. Jazz states that these batches must be given intramuscularly only and NOT intravenously. Batch 187K may be given either intramuscularly or intravenously via tubing with a 0.2-micron, low-protein-binding, in-line filter. Use 5-micron filter needles when withdrawing Erwinaze from vials. The most recent letter with further details can be found at and


Updated June 20, 2018 by Leslie Jensen, PharmD, Drug Information Specialist. Created October 11, 2016 by Elyse MacDonald, PharmD, MS, BCPS. Copyright 2018, Drug Information Service, University of Utah, Salt Lake City, UT.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.