Drug Interactions between Tadliq and terbutaline
This report displays the potential drug interactions for the following 2 drugs:
- Tadliq (tadalafil)
- terbutaline
Interactions between your drugs
terbutaline tadalafil
Applies to: terbutaline and Tadliq (tadalafil)
Consumer information for this interaction is not currently available.
MONITOR: Coadministration with tadalafil may increase the plasma concentrations of ethinyl estradiol and/or terbutaline. The mechanism of the interaction has not been fully elucidated but may involve inhibition of gut sulphation by tadalafil. At steady-state, tadalafil (40 mg once daily) increased ethinyl estradiol systemic exposure (AUC) by 26% and peak plasma concentration (Cmax) by 70% compared to an oral contraceptive taken with placebo. A similar increase may be expected with oral administration of terbutaline. The clinical significance of these findings is unknown.
MANAGEMENT: Clinicians should consider the potential for interaction during concomitant administration of tadalafil with ethinyl estradiol and/or terbutaline. If coadministration is required, caution and clinical monitoring is advisable. Individual product labeling should be consulted for further guidance.
Drug and food/lifestyle interactions
tadalafil food/lifestyle
Applies to: Tadliq (tadalafil)
Tadalafil can lower blood pressure, and combining it with alcohol may further increase this effect. You may be more likely to experience symptoms such as dizziness, lightheadedness, fainting, flushing, headache, and heart palpitations. You should avoid or limit the use of alcohol to not more than 4 alcohol-containing drinks during a small period of time while being treated with tadalafil, and use caution when getting up from a sitting or lying position. You may also want to avoid drinking large amounts of grapefruit juice, since it may increase the blood levels and effects of tadalafil. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
terbutaline food/lifestyle
Applies to: terbutaline
Both terbutaline and caffeine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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