Can you take Sodium polystyrene sulfonate with Zatean-PN Plus?
1 drug interaction and 8 additional warnings found for the following 2 drugs:
- sodium polystyrene sulfonate
- Zatean-PN Plus (multivitamin, prenatal)
Drug interactions
Moderate drug interactions
Moderate:
sodium polystyrene sulfonate multivitamins, prenatal
Applies to: sodium polystyrene sulfonate and Zatean-PN Plus (multivitamin, prenatal)
Sodium polystyrene sulfonate can bind to calcium, iron, magnesium, and other minerals in the gastrointestinal tract. This may inactivate both sodium polystyrene sulfonate and the mineral it binds to and reduce the effectiveness of both medications. To avoid or minimize the interaction, the dosing times of sodium polystyrene sulfonate and multivitamins, prenatal should be separated by several hours. Talk to your doctor if you have any questions or concerns, or if you have trouble separating the dosing times. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Food/lifestyle interactions
Moderate food/lifestyle interactions
Moderate:
sodium polystyrene sulfonate Food/Lifestyle
Applies to: sodium polystyrene sulfonate
Foods high in potassium such as orange juice and other fruit juices may reduce the effectiveness of sodium polystyrene sulfonate in treating your condition. Do not mix sodium polystyrene sulfonate in fruit juice or drink fruit juice with it. Also, sodium polystyrene sulfonate may interfere with the absorption of other medications that you take by mouth, including both prescription medications such as antibiotics, blood pressure/heart medications and blood thinners, and over-the-counter products such as antacids and laxatives. This can lead to lower blood levels and reduced effects if you take them too closely together with sodium polystyrene sulfonate. It is recommended that you separate the dosing of sodium polystyrene sulfonate from other oral medications by at least 3 hours whenever possible. This interval should be increased to 6 hours if you have gastroparesis or other conditions that cause delayed emptying of food from the stomach into the intestine. Talk to your doctor or pharmacist if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Moderate:
multivitamins, prenatal Food/Lifestyle
Applies to: Zatean-PN Plus (multivitamin, prenatal)
Food may reduce the absorption and blood levels of multivitamins, prenatal. In addition, some oral medications can also interfere with multivitamins, prenatal absorption into the bloodstream, which may make the medication less effective in treating your condition. Likewise, multivitamins, prenatal may interfere with the absorption of other orally administered medications. You should take multivitamins, prenatal on an empty stomach at least one hour before or two hours after a meal. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. Talk to your doctor or pharmacist if you have questions about how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Moderate:
sodium polystyrene sulfonate multivitamins with minerals
Applies to: sodium polystyrene sulfonate
Sodium polystyrene sulfonate can bind to calcium, iron, magnesium, and other minerals in the gastrointestinal tract. This may inactivate both sodium polystyrene sulfonate and the mineral it binds to and reduce the effectiveness of both medications. To avoid or minimize the interaction, the dosing times of sodium polystyrene sulfonate and multivitamins with minerals should be separated by several hours. Talk to your doctor if you have any questions or concerns, or if you have trouble separating the dosing times. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Disease interactions
5 potential interactions Applies to: 5 conditions, including High Blood Pressure, Heart Failure, Hypokalemia, Fluid Retention, and Intestinal Obstruction.
Fluid Retention
Major:
sodium polystyrene sulfonate
Sodium polystyrene sulfonate has a major potential interaction with Fluid Retention.
The use of sodium polystyrene sulfonate is associated with an elevation in sodium. Therapy with sodium polystyrene sulfonate should be administered cautiously in patients with conditions that might be exacerbated by additional sodium such as severe congestive heart failure, severe hypertension, or marked edema. Compensatory restriction of sodium intake from other sources may be indicated.
Heart Failure
Major:
sodium polystyrene sulfonate
Sodium polystyrene sulfonate has a major potential interaction with Heart Failure.
The use of sodium polystyrene sulfonate is associated with an elevation in sodium. Therapy with sodium polystyrene sulfonate should be administered cautiously in patients with conditions that might be exacerbated by additional sodium such as severe congestive heart failure, severe hypertension, or marked edema. Compensatory restriction of sodium intake from other sources may be indicated.
High Blood Pressure
Major:
sodium polystyrene sulfonate
Sodium polystyrene sulfonate has a major potential interaction with High Blood Pressure.
The use of sodium polystyrene sulfonate is associated with an elevation in sodium. Therapy with sodium polystyrene sulfonate should be administered cautiously in patients with conditions that might be exacerbated by additional sodium such as severe congestive heart failure, severe hypertension, or marked edema. Compensatory restriction of sodium intake from other sources may be indicated.
Hypokalemia
Major:
sodium polystyrene sulfonate
Sodium polystyrene sulfonate has a major potential interaction with Hypokalemia.
The use of sodium polystyrene sulfonate is contraindicated in patients with hypokalemia. Serious potassium deficiency can occur from therapy with sodium polystyrene sulfonate. Sodium polystyrene sulfonate exchanges sodium ions for potassium ions in the intestine or colon. Monitoring serum potassium levels carefully and evaluating the patient's clinical condition and electrocardiogram may be necessary.
Intestinal Obstruction
Major:
sodium polystyrene sulfonate
Sodium polystyrene sulfonate has a major potential interaction with Intestinal Obstruction.
The use of sodium polystyrene sulfonate is contraindicated in patients with obstructive bowel disease. Cases of intestinal necrosis, which may be fatal, and other serious gastrointestinal adverse events (bleeding, ischemic colitis, perforation) have been reported in association with sodium polystyrene sulfonate use. Therapy with this agent should be avoided in patients who have not had a bowel movement post-surgery, and patients who are at risk of developing constipation or impaction. Therapy with sodium polystyrene sulfonate should be discontinued in patients who develop constipation during treatment.
More resources
sodium polystyrene sulfonate
A total of 183 drugs are known to interact with sodium polystyrene sulfonate.
- Sodium polystyrene sulfonate is in the drug class cation exchange resins.
- Sodium polystyrene sulfonate is used to treat Hyperkalemia.
Zatean-PN Plus
A total of 172 drugs are known to interact with Zatean-PN Plus.
- Zatean-pn plus is in the following drug classes: iron products, vitamin and mineral combinations.
- Zatean-pn plus is used to treat Vitamin/Mineral Supplementation during Pregnancy/Lactation.
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.