Can you take Santyl with Silver nitrate topical?
1 drug interaction and 2 additional warnings found for the following 2 drugs:
- Santyl (collagenase topical)
- silver nitrate topical
Drug interactions
Moderate drug interactions
Moderate:
collagenase topical silver nitrate topical
Applies to: Santyl (collagenase topical) and silver nitrate topical
Talk to your doctor before using silver nitrate topical together with collagenase topical. Silver nitrate topical can reduce the effects of collagenase topical when applied to the same site. Silver nitrate topical should generally not be used on wounds treated with collagenase topical unless specifically directed by your doctor. If silver nitrate topical has been used, the site should be carefully cleansed by repeated washings with normal saline before application of collagenase topical. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Food/lifestyle interactions
No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Disease interactions
2 potential interactions Applies to: 2 conditions, including Hyponatremia and Electrolyte Abnormalities.
Electrolyte Abnormalities
Moderate:
silver nitrate topical
Silver nitrate topical has a moderate potential interaction with Electrolyte Abnormalities.
Electrolyte abnormalities of hyponatremia and hypochloremia have resulted from prolonged use of silver nitrate or application of wet dressings to extensive dermal areas. Sodium and chloride leech into dressings. Therapy with silver nitrate dressings should be applied cautiously in patients with or predisposition to electrolyte abnormalities. Clinical monitoring of electrolytes is recommended and electrolyte replacement as indicted.
Hyponatremia
Moderate:
silver nitrate topical
Silver nitrate topical has a moderate potential interaction with Hyponatremia.
Electrolyte abnormalities of hyponatremia and hypochloremia have resulted from prolonged use of silver nitrate or application of wet dressings to extensive dermal areas. Sodium and chloride leech into dressings. Therapy with silver nitrate dressings should be applied cautiously in patients with or predisposition to electrolyte abnormalities. Clinical monitoring of electrolytes is recommended and electrolyte replacement as indicted.
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More resources
Santyl
A total of 5 drugs are known to interact with Santyl.
- Santyl is in the drug class topical debriding agents.
- Santyl is used to treat Keratosis.
silver nitrate topical
A total of 51 drugs are known to interact with silver nitrate topical.
- Silver nitrate topical is in the drug class antiseptic and germicides.
- Silver nitrate topical is used to treat the following conditions:
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.