Drug Interactions between Prograf and Zortress
This report displays the potential drug interactions for the following 2 drugs:
- Prograf (tacrolimus)
- Zortress (everolimus)
Interactions between your drugs
No interactions were found between Prograf and Zortress. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Prograf
A total of 835 drugs are known to interact with Prograf.
- Prograf is in the drug class calcineurin inhibitors.
- Prograf is used to treat the following conditions:
Zortress
A total of 516 drugs are known to interact with Zortress.
- Zortress is in the following drug classes: mTOR inhibitors, selective immunosuppressants.
- Zortress is used to treat the following conditions:
Drug and food interactions
tacrolimus food
Applies to: Prograf (tacrolimus)
Tacrolimus should be taken on a consistent schedule before or after you eat at the same times each day. Grapefruit and grapefruit juice may increase the amount of tacrolimus in your body. This can lead to potentially dangerous side effects and should be avoided. If you are already consuming grapefruit products, do not increase or decrease the amount of these products in your diet without first talking to your doctor.
everolimus food
Applies to: Zortress (everolimus)
Grapefruit juice can increase the blood levels and effects of everolimus. You should not drink grapefruit juice or eat grapefruits during your treatment with everolimus. Orange juice is not expected to interact.
Therapeutic duplication warnings
Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.
Macrolide immunosuppressants
Therapeutic duplication
The recommended maximum number of medicines in the 'macrolide immunosuppressants' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'macrolide immunosuppressants' category:
- Prograf (tacrolimus)
- Zortress (everolimus)
Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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