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Drug Interactions between prednisone and Questran

This report displays the potential drug interactions for the following 2 drugs:

  • prednisone
  • Questran (cholestyramine)

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Interactions between your drugs


cholestyramine predniSONE

Applies to: Questran (cholestyramine) and prednisone

Bile acid binding resins such as cholestyramine, colestipol, and colesevelam may interfere with the absorption of predniSONE and reduce its levels in the bloodstream. This may make the medication less effective in treating your condition. To minimize the possibility of interaction, it is recommended that you separate the dosing times of the bile acid binding resin and other oral medications. If you are taking cholestyramine or colestipol, you should take predniSONE at least 1 hour before or 4 to 6 hours after the cholestyramine or colestipol dose. If you are taking colesevelam, you should take predniSONE at least 4 hours before the colesevelam dose, or separate the dosing times by as much as possible if a 4 hour interval is not achievable. Talk to your doctor or pharmacist if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

No interactions were found. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.