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Drug Interactions between prazosin and vimseltinib

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

prazosin vimseltinib

Applies to: prazosin and vimseltinib

Consumer information for this interaction is not currently available.

GENERALLY AVOID: Coadministration with vimseltinib may increase the plasma concentrations of drugs that are substrates of the breast cancer resistance protein (BCRP) efflux transporter. The proposed mechanism, based on in vitro data, is decreased clearance due to inhibition of BCRP-mediated intestinal and/or hepatic transport by vimseltinib. Clinical data are not available.

MANAGEMENT: Concomitant use of vimseltinib with BCRP substrates should generally be avoided. If coadministration is considered necessary, the individual product labeling of the BCRP substrate should be consulted for specific guidance.

Drug and food interactions

Moderate

prazosin food

Applies to: prazosin

Ask your doctor before using prazosin together with ethanol (alcohol). Using prazosin with ethanol (alcohol) can lower your blood pressure. This can cause dizziness or feeling like you might pass out, especially when getting up from a sitting or lying position. This may be more likely to occur when you first start taking either of these medications. You may need a dose adjustment or need your blood pressure checked more often if you take both medications. You may develop flushing, warmth or redness under your skin or tingly feeling after alcohol intake (especially in you are of Asian descent) and should be advised to avoid alcohol or limit your intake. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer