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Drug Interactions between praziquantel and Targretin

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

praziquantel bexarotene

Applies to: praziquantel and Targretin (bexarotene)

Bexarotene may reduce the blood levels of praziquantel, which may make the medication less effective in some cases. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe an alternative to praziquantel that you can take with bexarotene, or you may need to discontinue bexarotene for some time before you begin taking praziquantel. Contact your doctor if your symptoms worsen or your condition changes. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

praziquantel food

Applies to: praziquantel

Food can enhance the levels of praziquantel in your body. To ensure maximal oral absorption, praziquantel should be administered with or immediately after a meal. This will make it easier for your body to absorb the medication. If you are receiving therapy with praziquantel you should avoid grapefruits and grapefruit juice. Grapefruit can raise the levels of praziquantel in your body and increase side effects of dizziness, abdominal discomfort, and nausea.. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.

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Moderate

bexarotene food

Applies to: Targretin (bexarotene)

Food helps with the absorption of bexarotene from the gastrointestinal tract into the blood stream. You should take each dose the same time everyday with a meal. Avoid consuming large amounts of grapefruit or grapefruit juice during treatment, since doing so may increase the blood levels of bexarotene. Talk to your doctor or pharmacist if you have any questions or concerns about your medication. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.