Drug Interactions between polythiazide / prazosin and verteporfin

Before taking polythiazide, tell your doctor if you also use prazosin. You may need dose adjustments or special tests in order to safely take both medications together. The blood pressure lowering effects of this combination may be additive. You should take prazosin at bedtime and to notify your doctor if have dizziness or feel faint. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Before receiving verteporfin, you should let your doctor know if you are currently using or have recently used prazosin. Combining these medications may decrease the effectiveness of verteporfin in treating your eye condition. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Using verteporfin together with polythiazide may cause an increase in photosensitivity reactions, which could cause your skin to burn when exposed to light. Check with your doctor to see if you should temporarily withhold any of your medications before and after treatment with verteporfin. You should avoid exposure of skin or eyes to sunlight or bright indoor lights (examination lamps, operating room lamps, tanning beds, lights at close proximity) for 5 days after treatment with verteporfin. If you must go outdoors in the daylight during this 5-day time frame it is important to protect your skin and eyes by wearing protective clothing and dark sunglasses, even if you cannot see the sun (e.G., cloudy day). Exposing your skin to normal indoor lighting is helpful as it will help your body get rid of verteporfin more quickly, so you do not need to stay inside in the dark. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.