Drug Interactions between pentamidine and semaglutide

Pentamidine can sometimes affect blood glucose levels. Both hyperglycemia (high blood glucose) and hypoglycemia (low blood glucose) have been reported. The risk is greater when the medication is given by injection than when given by oral inhalation. Patients with reduced kidney function, such as the elderly, may also be at greater risk for developing these problems. Your blood glucose should be closely monitored during treatment with pentamidine so that your diabetic regimen may be adjusted, if needed. Let your doctor know if you experience hyperglycemia or hypoglycemia, or if you notice a loss of blood glucose control. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.