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Drug Interactions between Parsabiv and Sensipar

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

cinacalcet etelcalcetide

Applies to: Sensipar (cinacalcet) and Parsabiv (etelcalcetide)

Using etelcalcetide together with cinacalcet may significantly decrease the calcium levels in your blood. It is not recommended to start etelcalcetide until 7 days after stopping cinacalcet. Talk to your doctor if you have any questions or concerns. Your doctor may already be aware of the risks and has taken appropriate precautions and is monitoring you closely for any potential complications. Contact your doctor if your condition changes or if you experience symptoms of hypocalcemia (low blood calcium) such as numbness or tingling around your mouth, uncontrolled muscle movements, irritability, depression, irregular heartbeats, or any increased sensitivity. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

cinacalcet food

Applies to: Sensipar (cinacalcet)

Food can enhance the levels of cinacalcet in your body. Cinacalcet should be taken just after eating food. Do not take it on an empty stomach. This will make it easier for your body to absorb the medication. Do not crush, chew, or break the tablets. Swallow them whole.

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Therapeutic duplication warnings

Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.

Duplication

Calcimimetics

Therapeutic duplication

The recommended maximum number of medicines in the 'calcimimetics' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'calcimimetics' category:

  • Parsabiv (etelcalcetide)
  • Sensipar (cinacalcet)

Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.