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Drug Interactions between Oxsoralen and verteporfin

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

methoxsalen topical verteporfin

Applies to: Oxsoralen (methoxsalen topical) and verteporfin

Using verteporfin together with methoxsalen topical may cause an increase in photosensitivity reactions, which could cause your skin to burn when exposed to light. Check with your doctor to see if you should temporarily withhold any of your medications before and after treatment with verteporfin. You should avoid exposure of skin or eyes to sunlight or bright indoor lights (examination lamps, operating room lamps, tanning beds, lights at close proximity) for 5 days after treatment with verteporfin. If you must go outdoors in the daylight during this 5-day time frame it is important to protect your skin and eyes by wearing protective clothing and dark sunglasses, even if you cannot see the sun (e.G., cloudy day). Exposing your skin to normal indoor lighting is helpful as it will help your body get rid of verteporfin more quickly, so you do not need to stay inside in the dark. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.

Duplication

Photochemotherapeutic agents

Therapeutic duplication

The recommended maximum number of medicines in the 'photochemotherapeutic agents' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'photochemotherapeutic agents' category:

  • Oxsoralen (methoxsalen topical)
  • verteporfin

Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.