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Drug Interactions between Nylia 1 / 35 and theophylline

This report displays the potential drug interactions for the following 2 drugs:

  • Nylia 1/35 (ethinyl estradiol/norethindrone)
  • theophylline

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Interactions between your drugs

Moderate

theophylline ethinyl estradiol

Applies to: theophylline and Nylia 1 / 35 (ethinyl estradiol / norethindrone)

Ethinyl estradiol may increase the blood levels and effects of theophylline. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if you develop nausea, vomiting, diarrhea, headache, restlessness, insomnia, seizures, heart palpitations, and/or irregular heartbeat, as these may be signs and symptoms of excessive theophylline levels. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

theophylline norethindrone

Applies to: theophylline and Nylia 1 / 35 (ethinyl estradiol / norethindrone)

Norethindrone may increase the blood levels and effects of theophylline. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if you develop nausea, vomiting, diarrhea, headache, restlessness, insomnia, seizures, heart palpitations, and/or irregular heartbeat, as these may be signs and symptoms of excessive theophylline levels. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

theophylline food

Applies to: theophylline

Both smoking and excessive caffeine consumption can alter the blood levels of theophylline, which may affect the dosing. Tobacco and marijuana smoke (including secondhand exposure) generally reduces, while caffeine increases, blood levels. In addition, caffeine is a stimulant and may add to the side effects of theophylline such as headache, insomnia, and increases in blood pressure and heart rate. It is best to avoid smoking and to limit caffeine consumption during theophylline therapy. Talk to a healthcare professional if you have any questions or concerns. If you start smoking or undergo smoking cessation, your doctor may need to monitor your blood levels more closely to determine if you need a dose adjustment of theophylline. You should stop taking theophylline and seek medical attention if you experience potential signs and symptoms of excessive drug levels such as nausea, vomiting, persistent headache, insomnia, and rapid heartbeat. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

When theophylline is given with enteral (tube) feedings, blood levels may be decreased due to interference with its absorption. This may reduce the effectiveness of the medication. To minimize potential for interaction, you may interrupt the feeding for one hour before and one hour after the theophylline dose. You may need more frequent blood tests to monitor theophylline levels.

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Moderate

norethindrone food

Applies to: Nylia 1 / 35 (ethinyl estradiol / norethindrone)

Grapefruit juice may increase the blood levels of certain medications such as norethindrone. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with norethindrone. However, if you have been regularly consuming grapefruit or grapefruit juice with the medication, then it is advisable for you to talk with your doctor before changing the amounts of these products in your diet, as this may alter the effects of your medication. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.

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Minor

ethinyl estradiol food

Applies to: Nylia 1 / 35 (ethinyl estradiol / norethindrone)

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

For clinical details see professional interaction data.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.