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Drug Interactions between NutriSource and pivmecillinam

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

pivmecillinam guar gum

Applies to: pivmecillinam and NutriSource (guar gum)

Consumer information for this interaction is not currently available.

GENERALLY AVOID: Concurrent administration of guar gum may decrease the plasma levels of orally administered penicillins by reducing their absorption. In a study of 10 healthy volunteers administered phenoxymethyl penicillin with and without guar gum, both the peak serum concentration and the area under the serum concentration-time curve of penicillin were found to be significantly reduced by the gum.

MANAGEMENT: The use of guar gum should preferably be avoided during oral penicillin therapy. If these agents must be used together, separating the times of administration by as much as possible may help but has not been studied.

Drug and food interactions

Moderate

guar gum food

Applies to: NutriSource (guar gum)

Guar gum may interact with other medications if given at the same time. This can cause your other medications to become less effective. In general, all oral medications should be administered at least 2 hours before or 2 hours after dosing of guar gum. Take guar gum with a full glass (at least 8 ounces) of cool water or another liquid. Taking guar gum without enough liquid may cause it to swell in the throat and cause choking.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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