Drug interactions between nintedanib and pirfenidone
Interactions between your drugs
- Nintedanib is in the drug class multikinase inhibitors.
- Nintedanib is used to treat Idiopathic Pulmonary Fibrosis.
- Pirfenidone is a member of the drug class miscellaneous uncategorized agents.
- Pirfenidone is used to treat Idiopathic Pulmonary Fibrosis.
Drug and food interactions
Applies to: pirfenidone
Pirfenidone should be taken with food to help reduce dizziness and gastrointestinal side effects such as diarrhea, nausea, vomiting, and upset stomach. Avoid smoking during treatment, as cigarette smoking can reduce the blood levels and effects of pirfenidone. If you are a smoker, you should try to quit smoking before starting treatment. Talk to your doctor or pharmacist if you have any questions or concerns, or need help in finding a smoking cessation program. You should also avoid consuming grapefruit or grapefruit juice while taking pirfenidone, as it may increase blood levels of the medication and lead to more side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Applies to: nintedanib
Food may help the absorption of nintedanib. You should take this medication with food and swallow it whole with liquid. Chewing or crushing the medication can leave a bitter taste.
Therapeutic duplication warnings
No therapeutic duplications were found for your selected drugs.
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
Do not stop taking any medications without consulting your healthcare provider.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.