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Drug interactions between Neupro and Sinemet

Results for the following 2 drugs:
Neupro (rotigotine)
Sinemet (carbidopa/levodopa)

Interactions between your drugs

There were no interactions found in our database between Neupro and Sinemet. However, this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

Neupro

A total of 591 drugs (4193 brand and generic names) are known to interact with Neupro.

Sinemet

A total of 751 drugs (5719 brand and generic names) are known to interact with Sinemet.

Drug and food interactions

Moderate

levodopa food

Applies to: Sinemet (carbidopa / levodopa)

Alcohol can increase the nervous system side effects of levodopa such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with levodopa. You may experience reduced effectiveness of levodopa in the presence of foods or enteral (tube) feedings with a high protein content. This may make the symptoms of Parkinson's disease worse. Talk with your doctor or nutrition counselor about the best foods to eat while you are taking this medication. Contact your doctor if your condition changes.

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Moderate

rotigotine food

Applies to: Neupro (rotigotine)

Alcohol can increase the nervous system side effects of rotigotine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with rotigotine. Do not use more than the recommended dose of rotigotine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.

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Therapeutic duplication warnings

No therapeutic duplications were found for your selected drugs.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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