Drug Interactions between mitotane and Synalgos-DC
This report displays the potential drug interactions for the following 2 drugs:
- mitotane
- Synalgos-DC (aspirin/caffeine/dihydrocodeine)
Interactions between your drugs
mitotane dihydrocodeine
Applies to: mitotane and Synalgos-DC (aspirin / caffeine / dihydrocodeine)
Mitotane may reduce the blood levels of dihydrocodeine, which may make dihydrocodeine less effective in treating your condition. Additionally, if you have been receiving treatment with dihydrocodeine, adding mitotane may cause you to experience unpleasant withdrawal symptoms such as excessive sweating, chills, flushing, restlessness, irritability, anxiety, tremor, rapid heartbeat and nausea. On the other hand, if you have been receiving both medications, suddenly discontinuing mitotane may increase the blood levels of dihydrocodeine, which could increase or prolong its adverse effects. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
aspirin caffeine
Applies to: Synalgos-DC (aspirin / caffeine / dihydrocodeine) and Synalgos-DC (aspirin / caffeine / dihydrocodeine)
Information for this minor interaction is available on the professional version.
Drug and food interactions
mitotane food
Applies to: mitotane
High fat food significantly enhances the absorption of mitotane. You should take each dose of mitotane with a full meal containing high fat (e.G., containing milk, chocolate, or oil) and with a full glass of water. Taking mitotane on an empty stomach may lead to inadequate blood levels and reduced effectiveness of the medication. Talk to your doctor if you have questions or have difficulty taking mitotane with food. It is best to avoid or limit the consumption of alcohol, as it can increase drowsiness or other nervous system side effects of mitotane. You should also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
aspirin food
Applies to: Synalgos-DC (aspirin / caffeine / dihydrocodeine)
Ask your doctor before using aspirin together with ethanol (alcohol). Do not drink alcohol while taking aspirin. Alcohol can increase your risk of stomach bleeding caused by aspirin. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
caffeine food
Applies to: Synalgos-DC (aspirin / caffeine / dihydrocodeine)
Information for this minor interaction is available on the professional version.
aspirin food
Applies to: Synalgos-DC (aspirin / caffeine / dihydrocodeine)
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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