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Drug Interactions between Minizide and mixed grass pollens allergen extract

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

prazosin mixed grass pollens allergen extract

Applies to: Minizide (polythiazide / prazosin) and mixed grass pollens allergen extract

Using mixed grass pollens allergen extract together with prazosin may not be advisable. Immunotherapy with mixed grass pollens allergen extract can sometimes cause severe, even potentially life-threatening allergic reactions that require emergency treatment with epinephrine, and medications like prazosin can interfere with the body's response to epinephrine and significantly reduce its effectiveness. Talk to your doctor if you have any questions or concerns. Stop using mixed grass pollens allergen extract, administer epinephrine, and seek immediate medical attention if signs and symptoms of an allergic reaction develop such as trouble breathing, swallowing, or speaking; throat tightness or swelling; dizziness, lightheadedness, or fainting; rapid or weak heartbeat; severe stomach cramps or pain; vomiting or diarrhea; and/or severe flushing or itching. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

prazosin polythiazide

Applies to: Minizide (polythiazide / prazosin) and Minizide (polythiazide / prazosin)

Before taking polythiazide, tell your doctor if you also use prazosin. You may need dose adjustments or special tests in order to safely take both medications together. The blood pressure lowering effects of this combination may be additive. You should take prazosin at bedtime and to notify your doctor if have dizziness or feel faint. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

polythiazide mixed grass pollens allergen extract

Applies to: Minizide (polythiazide / prazosin) and mixed grass pollens allergen extract

Using mixed grass pollens allergen extract together with polythiazide may not be advisable. Immunotherapy with mixed grass pollens allergen extract can sometimes cause severe, even potentially life-threatening allergic reactions that require emergency treatment with epinephrine, and medications like polythiazide can potentiate the body's response to epinephrine and significantly increase its effects on blood pressure and heart rate as well as serious and potentially fatal irregular heart rhythms. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

mixed grass pollens allergen extract food

Applies to: mixed grass pollens allergen extract

Consuming food or beverage during or immediately after using mixed grass pollens allergen extract may reduce the amount of allergen extract available for absorption from tissues under the tongue into the blood stream. Food or beverage should not be taken with, or for at least 5 minutes after, using mixed grass pollens allergen extract. Use of alcohol with mixed grass pollens allergen extract may increase the risk and severity of allergic reactions that can sometimes occur during treatment with mixed grass pollens allergen extract. Potentially life-threatening or fatal reactions may occur. Talk to your doctor if you have any questions or concerns. Stop using mixed grass pollens allergen extract, administer epinephrine, and seek immediate medical attention if signs and symptoms of an allergic reaction develop such as trouble breathing, swallowing, or speaking; throat tightness or swelling; dizziness, lightheadedness, or fainting; rapid or weak heartbeat; severe stomach cramps or pain; vomiting or diarrhea; and/or severe flushing or itching. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

prazosin food

Applies to: Minizide (polythiazide / prazosin)

Ask your doctor before using prazosin together with ethanol. Using prazosin with ethanol can lower your blood pressure. This can cause dizziness or feeling like you might pass out, especially when getting up from a sitting or lying position. This may be more likely to occur when you first start taking either of these medications. You may need a dose adjustment or need your blood pressure checked more often if you take both medications. You may develop flushing, warmth or redness under your skin or tingly feeling after alcohol intake (especially in you are of Asian descent) and should be advised to avoid alcohol or limit your intake. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

polythiazide food

Applies to: Minizide (polythiazide / prazosin)

Polythiazide and ethanol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.