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Drug Interactions between mephobarbital and Norethin 1/50 M

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

norethindrone mephobarbital

Applies to: Norethin 1 / 50 M (mestranol / norethindrone) and mephobarbital

Mephobarbital may decrease the effectiveness of norethindrone. If you are using low-dose contraceptives, there is an increased risk of breakthrough bleeding and unintended pregnancy during combined therapy with mephobarbital. Alternative or additional methods of birth control should be used while taking mephobarbital. If you take hormone replacement for menopause, notify your doctor if you have decreased efficacy of your hormones. You may notice symptoms of increased hot flashes, vaginal dryness or menstrual abnormalities. It is important that you tell your healthcare provider about all other medications that you are using including vitamins and herbs. Do not stop using your medications without first talking to your doctor.

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Moderate

mephobarbital mestranol

Applies to: mephobarbital and Norethin 1 / 50 M (mestranol / norethindrone)

Mephobarbital may decrease the effectiveness of mestranol. If you are using low-dose contraceptives, there is an increased risk of breakthrough bleeding and unintended pregnancy during combined therapy with mephobarbital. Alternative or additional methods of birth control should be used while taking mephobarbital. If you take hormone replacement for menopause, notify your doctor if you have decreased efficacy of your hormones. You may notice symptoms of increased hot flashes, vaginal dryness or menstrual abnormalities. It is important that you tell your healthcare provider about all other medications that you are using including vitamins and herbs. Do not stop using your medications without first talking to your doctor.

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Drug and food interactions

Major

mephobarbital food

Applies to: mephobarbital

Ask your doctor before using mephobarbital together with ethanol, this can add to dizziness, drowsiness and other side effects of mephobarbital. Be careful if you drive or do activities that require you to be awake and alert. Talk with your doctor before using any medications together, or drinking alcohol with mephobarbital. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

norethindrone food

Applies to: Norethin 1 / 50 M (mestranol / norethindrone)

Grapefruit juice may increase the blood levels of certain medications such as norethindrone. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with norethindrone. However, if you have been regularly consuming grapefruit or grapefruit juice with the medication, then it is advisable for you to talk with your doctor before changing the amounts of these products in your diet, as this may alter the effects of your medication. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.

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Minor

mestranol food

Applies to: Norethin 1 / 50 M (mestranol / norethindrone)

Information for this minor interaction is available on the professional version.

Minor

norethindrone food

Applies to: Norethin 1 / 50 M (mestranol / norethindrone)

Information for this minor interaction is available on the professional version.

Minor

mestranol food

Applies to: Norethin 1 / 50 M (mestranol / norethindrone)

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.