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Drug Interactions between mephobarbital and nisoldipine

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

mephobarbital nisoldipine

Applies to: mephobarbital and nisoldipine

Mephobarbital may reduce the blood levels and effects of nisoldipine. Contact your doctor if your condition worsens or nisoldipine is no longer controlling your symptoms. Your doctor may be able to prescribe alternative treatments that do not interact, or you may need a dose adjustment or more frequent monitoring of your blood pressure and heart rate to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Drug and food interactions

Major

mephobarbital food

Applies to: mephobarbital

Ask your doctor before using mephobarbital together with ethanol (alcohol), this can add to dizziness, drowsiness and other side effects of mephobarbital. Be careful if you drive or do activities that require you to be awake and alert. Talk with your doctor before using any medications together, or drinking alcohol with mephobarbital. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Moderate

nisoldipine food

Applies to: nisoldipine

You should avoid or limit the consumption of grapefruit and grapefruit juice if you are receiving treatment with nisoldipine. Grapefruit juice can significantly increase the blood levels and effects of medications like nisoldipine. You may be more likely to experience side effects such as headache, low blood pressure, irregular heartbeat, swelling, and fluid retention. Talk to your doctor or pharmacist if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer