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Drug Interactions between Malarone and mefloquine

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

No interactions were found between Malarone and mefloquine. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Malarone

A total of 124 drugs are known to interact with Malarone.

mefloquine

A total of 424 drugs are known to interact with mefloquine.

Drug and food interactions

Moderate

mefloquine food

Applies to: mefloquine

Food can enhance the levels of mefloquine in your body. Take mefloquine immediately after a meal. This will make it easier for your body to absorb the medication. Take each dose with a full glass, at least 8 ounces (240 mL) of water. For children or those who have difficulty swallowing, mefloquine can be crushed and mixed with water or sugar water. Talk to your healthcare provider if swallowing the tablets is difficult.

Moderate

atovaquone food

Applies to: Malarone (atovaquone / proguanil)

Food significantly enhances the absorption of atovaquone. You should take each dose of atovaquone at the same time each day with a meal or a milky drink. If you receive enteral nutrition (tube feeding), take atovaquone with your feeding. Taking it on an empty stomach may lead to inadequate blood levels and reduced effectiveness of the medication. Talk to your doctor if you have questions or have difficulty taking atovaquone with food.

Therapeutic duplication warnings

Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.

Duplication

Antimalarials

Therapeutic duplication

The recommended maximum number of medicines in the 'antimalarials' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'antimalarials' category:

  • Malarone (atovaquone/proguanil)
  • mefloquine

Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer