Drug interactions between lisinopril and Rapaflo
Interactions between your drugs
lisinopril ↔ silodosin
Applies to:lisinopril and Rapaflo (silodosin)
Using silodosin and lisinopril together can have increased effects on your blood pressure. You may be more likely to experience side effects such as dizziness, weakness, headache, flushing, fainting, and irregular heartbeat, especially if you have been on lisinopril and are starting treatment with silodosin. These effects may also occur following a dose increase of silodosin or when silodosin is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. You may need a dose adjustment or more frequent monitoring of your blood pressure to safely use both medications. Taking the silodosin dose just before going to bed may help. Avoid driving or operating hazardous machinery until you know how these medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
Applies to: lisinopril
It is recommended that if you are taking lisinopril you should be advised to avoid moderately high or high potassium dietary intake. This can cause high levels of potassium in your blood. Do not use salt substitutes or potassium supplements while taking lisinopril, unless your doctor has told you to.
Applies to: Rapaflo (silodosin)
Taking silodosin with food can reduce the risk and/or severity of side effects. Therefore, silodosin should be administered with or immediately after a meal.
Therapeutic duplication warnings
No therapeutic duplications were found for your selected drugs.
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
Do not stop taking any medications without consulting your healthcare provider.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.