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Drug interactions between lisinopril and Medrol

Results for the following 2 drugs:
lisinopril
Medrol (methylprednisolone)

Interactions between your drugs

Moderate

methylPREDNISolone lisinopril

Applies to: Medrol (methylprednisolone) and lisinopril

MethylPREDNISolone may reduce the effects of lisinopril in lowering blood pressure. The interaction is most likely to occur when methylPREDNISolone is used for more than a week, since prolonged use can cause sodium and water retention. Let your doctor know if you experience sudden, unexplained weight gain or swelling of the hands, ankles, or feet. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

methylPREDNISolone food

Applies to: Medrol (methylprednisolone)

Grapefruit juice may increase the blood levels and effects of certain medications such as methylPREDNISolone. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with methylPREDNISolone. However, if you have been regularly consuming grapefruit or grapefruit juice with methylPREDNISolone, do not alter the amounts of these products in your diet without first talking to your doctor or other healthcare professional. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.

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Moderate

lisinopril food

Applies to: lisinopril

It is recommended that if you are taking lisinopril you should be advised to avoid moderately high or high potassium dietary intake. This can cause high levels of potassium in your blood. Do not use salt substitutes or potassium supplements while taking lisinopril, unless your doctor has told you to.

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Therapeutic duplication warnings

No therapeutic duplications were found for your selected drugs.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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