Drug Interactions between lindane topical and Promethazine with DM

Using dextromethorphan together with promethazine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Some of the medication in lindane topical can be absorbed through the skin into the bloodstream and produce seizures on rare occasions. The risk may be increased when used with other medications that can also cause seizures such as promethazine. This may be more likely to occur in very young children or the elderly; people undergoing alcohol or drug withdrawal; and those who have a history of seizures or a condition affecting the central nervous system such as a brain tumor or head trauma. Excessive or inappropriate use or accidental ingestion of lindane topical can also lead to seizures. Talk to a healthcare professional if you have any questions or concerns. You should follow closely the instructions for use of lindane topical given by the prescriber, and keep the product out of reach of children. Do not exceed the frequency and duration of use recommended on the product label or prescribed by the doctor. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.