Drug Interactions between LarkaDrin and Orvaten
This report displays the potential drug interactions for the following 2 drugs:
- LarkaDrin (acetaminophen/dichloralphenazone/isometheptene mucate)
- Orvaten (midodrine)
Interactions between your drugs
isometheptene mucate midodrine
Applies to: LarkaDrin (acetaminophen / dichloralphenazone / isometheptene mucate) and Orvaten (midodrine)
Using midodrine together with isometheptene mucate can increase the risk of hypertension. Midodrine may cause significant increases in blood pressure by constricting the blood vessels, and the risk for complications may be increased when used with other drugs that also affect blood pressure such as decongestants, stimulants, and certain medications for headache, glaucoma, or eye redness relief. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. Contact your doctor immediately if you experience symptoms that could indicate an acute increase in blood pressure, such as severe or throbbing headache, pounding in the ears, chest pain, and blurred vision. In some cases, sleeping with the head of the bed elevated or taking the last daily dose of midodrine 3 to 4 hours before bedtime may help lessen the effects on blood pressure. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
acetaminophen food
Applies to: LarkaDrin (acetaminophen / dichloralphenazone / isometheptene mucate)
Ask your doctor before using acetaminophen together with ethanol. This can cause serious side effects that affect your liver. Call your doctor immediately if you experience a fever, chills, joint pain or swelling, excessive tiredness or weakness, unusual bleeding or bruising, skin rash or itching, loss of appetite, nausea, vomiting, or yellowing of the skin or the whites of your eyes. If your doctor does prescribe these medications together, you may need a dose adjustment or special tests to safely take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
dichloralphenazone food
Applies to: LarkaDrin (acetaminophen / dichloralphenazone / isometheptene mucate)
Alcohol can increase the nervous system side effects of dichloralphenazone such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with dichloralphenazone. Do not use more than the recommended dose of dichloralphenazone, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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